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High DHEAS is associated with earlier pubertal events in girls but not in boys
(Oxford, 2017)
Context: Premature adrenarche (PA) has been associated with increased metabolic risk.
Objective: To describe the risk of precocious thelarche (PT; ,8 years), pubarche (PP; girls ,8 years,
boys ,9 years), and gonadarche ...
Bone mineral density in healthy female adolescents according to age, bone age and pubertal breast stage
(Bentham Open, 2011)
This study was designed to evaluate bone mineral density (BMD) in healthy female Brazilian adolescents in five groups looking at chronological age, bone age, and pubertal breast stage, and determining BMD behavior for each ...
Prenatal and pubertal testosterone exposure imprint permanent modifications in the prostate that predispose to the development of lesions in old Mongolian gerbils
(2017-03-01)
The prostate is an accessory sex gland that develops under precise androgenic control. It is known that hormonal imbalance may disrupt its development predisposing this gland to develop diseases during aging. Although the ...
Role of the Androgen Receptor Gene CAG Repeat Polymorphism on the Sequence of Pubertal Events and Adiposity in Girls with High Dehydroepiandrosterone Sulfate Level
(Elsevier USA, 2019)
Study Objective: The androgen receptor (AR) harbors a variable repeat number of glutamine residues codified by (CAG)n, which seems to inversely affect AR transcriptional activity. We assessed whether (CAG)n affects the ...
A Polygenic Risk Score Suggests Shared Genetic Architecture of Voice Break With Early Markers of Pubertal Onset in Boys.
Context: Voice break, as a landmark of advanced male puberty in genome-wide association studies (GWAS), has revealed that pubertal timing is a highly polygenic trait. Although voice break is easily recorded in large cohorts, ...