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Inactivation of tumor suppressor gene pten in early and advanced gallbladder cancer
(Biomed Central Ltd., 2015)
BACKGROUND:
PTEN is a tumor suppressor gene that regulates the PTEN/PI3k/AKT/mTOR pathway, which is frequently altered in human cancers including gallbladder cancer (GBC). To determine the frequency of PTEN expression in ...
Inactivation of tumor suppressor gene pten in early and advanced gallbladder cancer
(Biomed Central Ltd., 2015)
BACKGROUND:
PTEN is a tumor suppressor gene that regulates the PTEN/PI3k/AKT/mTOR pathway, which is frequently altered in human cancers including gallbladder cancer (GBC). To determine the frequency of PTEN expression in ...
Genetic and epi-genetic alterations of the PTEN gene : key in the relationship between type 2 diabetes and cancer
(Universidad Nacional de Misiones. Facultad de Ciencias Exactas, Químicas y Naturales. Secretaria de Investigación y Posgrado, 2021-10-15)
Cancer pathogenesis has been associated with genetic and epigenetic alterations that may lead to the inactivation or decrease of tumor-suppressor genes, such as the PTEN gene. In particular, alterations in the PI3K/PTEN ...
Expressão imunoistoquímica de EGFR e PTEN em displasias epiteliais orais
(Universidade Federal do Rio Grande do NorteBRUFRNPrograma de Pós-Graduação em Patologia OralOdontologia, 2014-02-12)
TNF-α induces vascular insulin resistance via positive modulation of PTEN and decreased Akt/eNOS/NO signaling in high fat diet-fed mice
(BioMed Central, 2016)
Abstract
Background
High fat diet (HFD) induces insulin resistance in various tissues, including the vasculature. HFD also increases plasma levels of TNF-α, a cytokine that ...
Estudo dos pólipos endometriais pela imunoexpressão das proteinas p53 e PTENStudy of endometrial polyps by immune expression of p53 and PTEN proteins
(Universidade Estadual Paulista (Unesp), 2016)
Rol patogénico del gen supresor de tumores PTEN en cáncer ovárico asociado a endometriosis
(Sociedad Médica de Santiago, 2006)
Single nucleotide polymorphism in PTEN-Long gene : a risk factor in chronic myeloid leukemia
(Elsevier, 2019-04-30)
The BCR-ABL1 oncogene is associated with chronic myeloid leukemia (CML) pathogenesis, but the molecular mechanisms that initiate leukemogenesis are still unclear. Cancer pathogenesis has been associated with genetic ...
Estudo dos pólipos endometriais pela imunoexpressão das proteinas p53 e PTEN
(Universidade Estadual Paulista (Unesp), 2016-02-19)
Objetivo: Avaliar os pólipos endometriais pela imunoexpressão das proteínas p53 e PTEN como fatores preditivos para riscos de pré-malignidade e malignidade. Pacientes e Métodos: Estudo transversal com amostra por conveniência, ...
Análise da expressão da proteína PTEN em carcinoma papilar de tireoide
(Universidade Federal de Minas GeraisUFMG, 2012-08-03)
PTEN (phosphatase and tensin homologue) is a tumor suppressor gene, located on chromosome 10q23.3. The gene negatively regulates the PI3K/Akt pathway, stimulating apoptosis and blocking the cell proliferation and cell ...