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Effectiveness, against tuberculosis, of pseudo-ternary complexes: Peptide-DNA-cationic liposome
(ElsevierSan Diego, 2012)
Síntese de pseudo-peptídeos contendo calcogenonucleosídeos via reações de UGI como potenciais inibidores do SARS-CoV-2
(Universidade Federal de Santa MariaBrasilQuímicaUFSMPrograma de Pós-Graduação em QuímicaCentro de Ciências Naturais e Exatas, 2023-03-30)
In this work, a reaction protocol was developed for a new class of pseudo-peptides through multicomponent reactions (MCR) of the Ugi’s four component reaction (U-4CR) type, starting from chalcogenonucleosides. The synthetic ...
Effectiveness, against tuberculosis, of pseudo-ternary complexes: Peptide-DNA-cationic liposome
(ACADEMIC PRESS INC ELSEVIER SCIENCESAN DIEGO, 2013-08-02)
We report the effects of a synthetic peptide designed to act as a nuclear localization signal on the treatment of tuberculosis. The peptide contains 21 amino acid residues with the following specific domains: nuclear ...
Andrimid production at low temperature by a psychrotolerant Serratia proteamaculans strain
(Springer, 2013-04)
Andrimid, a known non-ribosomal pseudo- peptide antibiotic, was isolated from a psychrotolerant Serratia proteamaculans strain. The antibiotic peptide was produced at low temperature (8 °C) in a 7.5 l BIOFLO 101 bioreactor ...
Improved pan-specific MHC class I peptide binding predictions using a novel representation of the MHC binding cleft environment
(Wiley, 2014-02)
Major histocompatibility complex (MHC) molecules play a key role in cell-mediated immune responses presenting bounded peptides for recognition by the immune system cells. Several in silico methods have been developed to ...
Evaluation Of Ops-agarose Pseudo-affinity Adsorption Igg(2a) Mouse Monoclonal Antibody
(ELSEVIER SCI LTDOXFORD, 2015)
Multicomponent reactions in the discovery of organocatalysts and the diversification of organocatalytic approaches
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Química - PPGQCâmpus São Carlos, 2015-06-19)
This thesis reports the development of multicomponent approaches directed to specific objectives: a) the discovery of new and efficient peptide-based catalyst for asymmetric
transformations and b) the synthesis of ...
Improved pan-specific MHC class I peptide-binding predictions using a novel representation of the MHC-binding cleft environment
(Wiley, 2014)
Major histocompatibility complex (MHC) molecules play a key role in cell-mediated immune responses presenting bounded peptides for recognition by the immune system cells. Several in silico Methods: have been developed to ...
Isomannide derivatives as new class of inhibitors for human kallikrein 7
(Elsevier B.V., 2012-10-01)
Human kallikrein 7 (KLK7) is a potential target for the treatment of skin inflammation and cancer. Despite its potential, few KLK7-specific small-molecule inhibitors have been reported in the literature. As an extension ...
Interaction between the C-Terminal Peptides of Tubulin and Tubulin S Detected with the Fluorescent Probe 4',6-Diamidino-2-Phenylindole
(1993)
The digestion of tubulin with subtilisin and the reassociation of the digestion products was followed by means of the fluorescent probe 4',6-diamidino-2-phenylindole (DAPI). The fluorescence spectra of DAPI bound to chicken ...