Buscar
Mostrando ítems 1-10 de 23
Role of peptide peptide interactions in aggregation: protonectins observed in equilibrium and replica exchange molecular dynamics simulations
(Amer Chemical Soc, 2015-04-07)
Protonectin (ILGTILGLLKGL-NH2), a peptide extracted from the venom of the wasp Agelaia pallipes pallipes, promotes mast cell degranulation activity, antibiosis against Gram-positive and -negative bacteria, and chemotaxis ...
Protonectin peptides target lipids, act at the interface and selectively kill metastatic breast cancer cells while preserving morphological integrity
(2021-11-01)
Despite the need for innovative compounds as antimicrobial and anticancer agents, natural sources of peptides remain underexplored. Protonectin (PTN), a cationic dodecapeptide of pharmacological interest, presents large ...
Protonectin (1-6): A novel chemotactic peptide from the venom of the social wasp Agelaia pallipes pallipes
(Pergamon-Elsevier B.V. Ltd, 2010-11-01)
Peptides constitute the largest group of Hymenoptera venom toxins; some of them interact with GPCR, being involved with the activation of different types of leukocytes, smooth muscle contraction and neurotoxicity. Most of ...
Protonectin (1-6): A novel chemotactic peptide from the venom of the social wasp Agelaia pallipes pallipes
(Pergamon-Elsevier B.V. Ltd, 2010-11-01)
Peptides constitute the largest group of Hymenoptera venom toxins; some of them interact with GPCR, being involved with the activation of different types of leukocytes, smooth muscle contraction and neurotoxicity. Most of ...
Isolation and sequence analysis of peptides from the venom of Protonectarina sylveirae (hymenoptera‐vespidae)
(1993-01-01)
Three new venom peptides were isolated from the Brazilian wasp; Protonectarina sylveirae and their complete amino acid sequences were determined by Edman degradation as well as by FAB‐mass spectrometry. One (P‐8) of them ...
Interações de peptídeos de cadeias curtas e bicamadas lipídicas: estudo biofísico e reflexos sobre a atividade biológica
(Universidade Estadual Paulista (Unesp), 2018-11-26)
O uso de peptídeos bioativos em antibioticoterapia tem dentre suas vantagens principais a reduzida possibilidade de desenvolvimento de resistência, uma vez que o alvo são os fosfolipídios constituintes da membrana celular. ...
Protonectin (1-6): A novel chemotactic peptide from the venom of the social wasp Agelaia pallipes pallipes
(Pergamon-Elsevier B.V. Ltd, 2014)
Estudo das interações de peptídeos antimicrobianos e sistemas miméticos de membrana por dinâmica molecular
(Universidade Estadual Paulista (Unesp), 2014-08-29)
Many peptides extracted from plants and animal secretions exhibit a broad spectrum of antimicrobial activity against bacteria gram-negative, gram-positive, fungi and parasites. Due this characteristic and the increasing ...