In order to preserve structure and function, proteins tend to preferentially conserve amino acids at particular sites along the sequence. Because mutations can affect structure and function, the question arises whether the ...

Protein Structure Prediction (PSP) can be considered one of the most challenging problems in Bioinformatics nowadays. When a protein is in its conformation state, the free energy is minimized. Evaluation of protein ...

Lipid-protein interactions play an essential role in the regulation of biological function of integral membrane proteins; however, the underlying molecular mechanisms are not fully understood. Here we explore the modulation ...

To evaluate the nutritional behaviour of simple and complex diets provided under different feeding regimes, a stochastic, dynamic and predictive simulation model was developed. Feed fractions, considered in the model were ...

One of the bottlenecks in biopharming is the scalability and modeling of batch cultures at bench scale, largely because bioreactors and mathematical models were originally designed for microbe cultures. Thus, a ...

This paper focuses on the prediction of the dimensionless retention time of proteins (DRT) in hydrophobic interaction chromatography (HIC) by means of mathematical models based, essentially, only on aminoacidic composition. ...

This paper focuses on the prediction of the dimensionless retention time of proteins (DRT) in hydrophobic interaction chromatography (HIC) by means of mathematical models based, essentially, only on aminoacidic composition. ...

A mathematical model, involving diffusion of extracellular compounds and cell interactions, has been adapted, in order to assess the quorum sensing process occurring in biofilms. Quorum sensing is a diffusion dependent ...