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Protein Carbonyl, But Not Malondialdehyde, Is Associated With ICU Mortality in Patients With Septic Shock
(2019-08-01)
Background: The objective of our study was to evaluate the association of serum malondialdehyde (MDA) and protein carbonyl concentration with intensive care unit (ICU) mortality in patients with septic shock. Methods: We ...
Protein carbonyl concentration as a biomarker for development and mortality in sepsis-induced acute kidney injury
(2018-01-25)
The objective of the present study was to evaluate protein carbonyl concentration as a predictor of AKI development in patients with septic shock and of renal replacement therapy (RRT) and mortality in patients with SAKI. ...
Serum thiamine concentration and oxidative stress as predictors of mortality in patients with septic shock
(Elsevier B.V., 2014-02-01)
Purpose: The purpose of the study is to determine the influence of serum thiamine, glutathione peroxidase (GPx) activity, and serum protein carbonyl concentrations in hospital mortality in patients with septic shock.Materials ...
Protein Carbonylation Is Related to Liver Damage in an Experimental Model of Obesity
(Federation Amer Soc Exp Biol, 2017-04-01)
Lipid damage is the best marker of oxidative injury during the cardiac remodeling process induced by tobacco smoke
(2018-11-16)
BACKGROUND: Oxidative stress is one potential mechanism that explain the direct effects of smoking on cardiac remodeling process. However, no study has compared different myocardial products of macromolecule oxidation after ...
Obligatory role in GTP hydrolysis for the amide carbonyl oxygen of the Mg2+-coordinating Thr of regulatory GTPases
(National Academy of Sciences, 2010-05-25)
When G-protein α subunits binds GTP and Mg2+, they transition from their inactive to their active conformation. This transition is accompanied by completion of the coordination shell of Mg2+ with electrons from six oxygens: ...
Relationship between prolonged sweetener consumption and chronic stress in the production of carbonylated proteins in blood lymphocytes
(Science Domain International, 2018)