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HMG‐Like chromosomal proteins in Trypanosoma cruzi
(1992)
HMG‐like chromosomal proteins from Truypansoma cruzi were studies. Four HMG‐like proteins, designated HMG A, HMGA‐B, HMG‐C, and HMG‐E, were isolated and found to have molecular weights of 35.5 kd, 27.5 kd, 21.8 kd and 10.4 ...
In vitro and in silico studies of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitory activity of the cowpea Gln-Asp-Phe peptide
(2018-09-01)
Previous studies have shown that cowpea protein positively interferes with cholesterol metabolism. In this study, we evaluated the ability of the fraction containing peptides of <3 kDa, as well as that of the Gln-Asp-Phe ...
IAF, QGF, and QDF peptides exhibit cholesterol-lowering activity through a statin-like HMG-CoA reductase regulation mechanism: In silico and in vitro approach
(2021-10-01)
In this study, in silico approaches are employed to investigate the binding mechanism of peptides derived from cowpea β-vignin and HMG-CoA reductase. With the obtained information, we designed synthetic peptides to evaluate ...
Desempenho do grupo de proteínas 1 de alta mobilidade (HMG1) e da interleucina 6 como preditores de desfechos resultantes do sangramento varicoso em pacientes com hepatopatia crônica avançada descompensada
(Universidade Federal de Minas GeraisBrasilMEDICINA - FACULDADE DE MEDICINAPrograma de Pós-Graduação em Ciências Aplicadas à Saúde do AdultoUFMG, 2019-08-06)
Introduction: Bleeding resulting from rupture of esophagogastric varices is considered a serious complication resulting from portal hypertension and potentially fatal in patients with advanced chronic liver disease. In ...
The Vicilin protein (Vigna radiata L.) of mung bean as a functional food Evidence of in vitro hypocholesterolemic activity
(Emerald Group Publishing Ltd, 2017-01-01)
Purpose - The hypocholesterolemic activity of legume vicilins and the structural homology among mung bean, soybean and adzuki bean vicilins (8S) suggest that this protein may play a role in lipid metabolism. Thus, in the ...