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The promiscuous phosphomonoestearase activity of Archaeoglobus fulgidus CopA, a thermophilic Cu+ transport ATPase
(Elsevier Science, 2016-07-14)
Membrane transport P-type ATPases display two characteristic enzymatic activities: a principal ATPase activity provides the driving force for ion transport across biological membranes, whereas a promiscuous secondary ...
Is Rk-682 A Promiscuous Enzyme Inhibitor? Synthesis And In Vitro Evaluation Of Protein Tyrosine Phosphatase Inhibition Of Racemic Rk-682 And Analogues
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIERPARIS, 2015)
Discovery of novel Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase inhibitors
(Pergamon-Elsevier B.V. Ltd, 2009-03-15)
Based on its essential role in the life cycle of Trypanosoma cruzi, the glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase (GAPDH) has been considered a promising target for the development of novel chemotherapeutic ...
Discovery of novel Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase inhibitors
(Pergamon-Elsevier B.V. Ltd, 2009-03-15)
Based on its essential role in the life cycle of Trypanosoma cruzi, the glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase (GAPDH) has been considered a promising target for the development of novel chemotherapeutic ...
Síntese e estudo in silico de derivados de naproxeno com potencial atividade anti-inflamatória
(Universidade Tecnológica Federal do ParanáCampo MouraoBrasilDepartamento Acadêmico de QuímicaLicenciatura em QuímicaUTFPR, 2016-06-30)
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the drugs most commonly used among therapeutic agents. However results of clinical studies indicate that adverse effects caused by these drugs include increased risk ...
Discovery of novel Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase inhibitors
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
Based on its essential role in the life cycle of Trypanosoma cruzi, the glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase (GAPDH) has been considered a promising target for the development of novel chemotherapeutic ...
First evidence of glutathione metabolism in Leptospira interrogans
(Elsevier Science Inc, 2019-11)
Background: Glutathione (GSH) plays a role as a main antioxidant metabolite in all eukaryotes and many prokaryotes. Most of the organisms synthesize GSH by a pathway involving two enzymatic reactions, each one consuming ...