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Prominin-1 (CD133) modulates the architecture and dynamics of microvilli
(Wiley Blackwell Publishing, Inc, 2018-11-14)
Prominin-1 is a cell surface biomarker that allows the identification of stem and cancer stemcells from different organs. It is also expressed in several differentiated epithelial and non-epithelial cells. Irrespective of ...
Early ciliary and prominin-1 dysfunctions precede neurogenesis impairment in a mouse model of type 2 diabetes
(Academic Press Inc Elsevier Science, 2017-12)
Diabetes mellitus (DM) is reaching epidemic conditions worldwide and increases the risk for cognition impairment and dementia. Here, we postulated that progenitors in adult neurogenic niches might be particularly vulnerable. ...
Effects of the oestrogen receptor antagonist Fulvestrant on expression of genes that affect organization of the epididymal epithelium
(Wiley-Blackwell, 2014-07-01)
The role of oestrogens in epididymal function is still unclear. Knockout of the oestrogen receptor ESR1 (Esr1-/-) or treatment with the anti-oestrogen Fulvestrant affect epididymal milieu and sperm motility. We investigated ...
Transcriptomic meta-analysis of sorted CD133+ stem cells and their analogues in cancer yields a set of common differentially expressed genes and overrepresented functional categories
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2019)
The use of stem cells has been exploited for their potential application in regenerative medicine due to their properties of self-renewal, proliferation, differentiation, and immunomodulation. The isolation of primitive ...
CD133 in breast cancer cells and in breast cancer stem cells as another target for immunotherapy
(Elsevier, 2016)
Breast cancer consists of a heterogeneous group of tumors with different features, biology and treatments. Cancer stem cells (CSCs) have been associated with an aggressive cellular behavior, resistance to chemotherapy and ...
PROM1 gene variations in Brazilian patients with macular dystrophy
(Taylor & Francis Inc, 2017)
Background: Although the pathogenicity of the prominin-1 (PROM1) gene has already been described as associated with autosomal dominant Stargardt disease, little is known about sequence variations in this gene. Purpose: The ...
Caracterización y rendimiento de células madre mesenquimales CD133+ y CD133- derivadas de tejido adiposo
Adipose-derived mesenchymal stem cells are adult multipotent cells that have shown
promising results in regenerative medicine. Heterogeneity among this cell group poses a
challenge for clinical application. The following ...
Endothelinergic cells in the subependymal region of mice
(Elsevier Science, 2010-03)
Endothelin (ET) is a small peptide that activates astrocyte proliferation, regulates proliferation and migration of embryonic neural precursor cells and stimulates glioblastoma growth. We found that in mouse brain, ET and ...
Differential expression of functional nucleoside transporters in non-differentiated and differentiated human endothelial progenitor cells
(W B SAUNDERS CO LTD, 2010)
Extracellular adenosine removal is via human equilibrative nucleoside transporters 1 (hENT1) and 2 (hENT2) in the endothelium, thus regulating adenosine-induced revascularization and angiogenesis. Since human endothelial ...