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Membrane effects of Cocoa Procyanidins in Liposomes and Jurkat T Cells
(Sociedad de Biología de Chile, 2004)
Interactions of flavan-3-ols and procyanidins with membranes: mechanisms and the physiological relevance
(Royal Society of Chemistry, 2015-01)
Flavonoids are a type of phenolic compound widely present in edible plants. A great number of health benefits have been ascribed to flavonoid consumption in the human population. However, the molecular mechanisms involved ...
Procyanidins can interact with Caco-2 cell membrane lipid rafts: involvement of cholesterol
(Elsevier Science, 2013-11)
Large procyanidins (more than three subunits) are not absorbed at the gastrointestinal tract but could exert local effects through their interactions with membranes. We previously showed that hexameric procyanidins (Hex), ...
Large procyanidins prevent bile acid-induced oxidant production and membrane-initiated ERK1/2, p38, and Akt activation in Caco-2 cells
(Elsevier Inc, 2012-01)
Procyanidins are oligomers of flavanol subunits present in large amounts in fruits and vegetables. Their consumption is associated with health benefits against colonic inflammation and colorectal cancer (CRC). Large ...
Dimeric procyanidins are inhibitors of NF-κB–DNA binding
(Pergamon-Elsevier Science Ltd, 2009-11)
Given the central role of the transcription factor NF-kB in inflammation, molecules that can inhibit NFkB are being actively investigated. The present work characterize potential interactions between dimeric procyanidins ...
Ascorbate protects (+)-catechin from oxidation both in a pure chemical system and human plasma
(Sociedad de Biología de Chile, 2000)
Dietary flavonoids: Role of (-)-epicatechin and related procyanidins in cell signaling
(Elsevier Science Inc., 2011-08)
Plant polyphenols are among the most abundant phytochemicals present in human diets. Increasing evidence supports the health-promoting effects of certain polyphenols, including flavonoids. This review discusses current ...
Impact of cocoa products intake on plasma and urine metabolites: a review of targeted and non-targeted studies in humans
(2019)
Cocoa is continuously drawing attention due to growing scientific evidence suggesting its effects on health. Flavanols and methylxanthines are some of the most important bioactive compounds present in cocoa. Other important ...
Chemometric Classification of Colombian Cacao Crops : Effects of Different Genotypes and Origins in Different Years of Harvest on Levels of Flavonoid and Methylxanthine Metabolites in Raw Cacao Beans
(MDPIGrupo de Investigación en Sustancias Bioactivas (GISB)Basilea, Suiza, 2022)