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Experimental gestational diabetes induces a pro-inflammatory and pro-oxidant environment in maternal and fetal livers
(Elsevier, 2019)
Gestational diabetes (GDM) is a prevalent disease associated with a pro-oxidant and pro-inflammatory environment and with adverse consequences to both the mother and the offspring. The fetal liver is highly exposed to ...
Mir-351-5p contributes to the establishment of a pro-inflammatory environment in the H9c2 cell line by repressing PTEN expression
(Springer, 2016-01-01)
The activated renin-angiotensin-aldosterone system modulates several metabolic pathways that contribute to left ventricular hypertrophy and heart failure. In this metabolic system, angiotensin II modulates heart ...
Volcanic ash from Puyehue-Cordón Caulle Volcanic Complex and Calbuco promote a differential response of pro-inflammatory and oxidative stress mediators on human conjunctival epithelial cells
(Academic Press Inc Elsevier Science, 2018-11)
Volcanic ash could pose a hazard to the ocular surface as it is constantly exposed to environmental particles. We exposed conjunctival cells to Puyehue-Cordón Caulle volcanic complex (PCCVC) or Calbuco ash particles and ...
Avaliação in vitro do efeito pró-inflamatório e oxidativo dos pesticidas mancozebe, clorotalonil e tiofanato metílico
(Universidade Federal de Santa MariaBrasilCiência e Tecnologia dos AlimentosUFSMPrograma de Pós-Graduação em Ciência e Tecnologia dos AlimentosCentro de Ciências Rurais, 2017-03-02)
Pesticides are widely used in agriculture and public health for pest control and prevention. The indiscriminate use of these compounds can trigger environmental contamination by pesticides and increase the risk of human ...
Avaliação in vitro do efeito pró-inflamatório e oxidativo dos pesticidas mancozebe, clorotalonil e tiofanato metílico
(Universidade Federal de Santa MariaBrasilCiência e Tecnologia dos AlimentosUFSMPrograma de Pós-Graduação em Ciência e Tecnologia dos AlimentosCentro de Ciências Rurais, 2017-03-02)
Pesticides are widely used in agriculture and public health for pest control and prevention. The indiscriminate use of these compounds can trigger environmental contamination by pesticides and increase the risk of human ...
Mir-513a-3p contributes to the controlling of cellular migration processes in the A549 lung tumor cells by modulating integrin beta-8 expression
(Springer, 2018-07-01)
Lung tumors are a frequent type of cancer in humans and a leading cause of death, and the late diagnostic contributes to high mortality rates. New therapeutic strategies are needed, and the heptapeptide angiotensin-(1-7) ...
Role of cyclooxygenase-2 in Trypanosoma cruzi survival in the early stages of parasite host-cell interaction
(Fundaco Oswaldo Cruz, 2015-04-01)
Chagas disease, caused by the intracellular protozoan Trypanosoma cruzi, is a serious health problem in Latin America. During this parasitic infection, the heart is one of the major organs affected. The pathogenesis of ...
A maternal diet enriched in olive oil prevents pro-inflammatory alterations in term placentas from diabetic pregnant women
(Elsevier Ireland, 2019)
Gestational diabetes mellitus (GDM) induces a pro-inflammatory intrauterine environment and alters placental function. Peroxisome proliferator-activated receptors (PPARs) are ligand activated transcription factors that ...
Induction of pro-inflammatory response of the placental trophoblast by Plasmodium falciparum infected erythrocytes and TNF.
(BioMed CentralGrupo MalariaReino Unido, 2019)
Glucose Promotes a Pro-Oxidant and Pro-Inflammatory Stromal Microenvironment Which Favors Motile Properties in Breast Tumor Cells
(Wiley, 2017)
Chronic inflammation and metabolic reprogramming have been proposed as hallmarks of cancer development. Currently, many of the functional clues between these two phenomena are studied under the integrative view of functional ...