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Prenatal ethanol exposure increases ethanol intake and reduces C-fos expression in infralimbic cortex of adolescent rats
(Elsevier Inc, 2012-12)
Prenatal ethanol exposure significantly increases later predisposition for alcohol intake, but the mechanisms associated with this phenomenon remain hypothetical. This study analyzed (Experiment 1) ethanol intake in ...
Prenatal exposure to ethanol during late gestation facilitates operant self-administration of the drug in 5-day-old rats
(Elsevier Science Inc, 2014-02)
Prenatal ethanol exposure modifies postnatal affinity to the drug, increasing the probability of ethanol use and abuse. The present study tested developing rats (5-day-old) in a novel operant technique to assess the degree ...
Prenatal ethanol exposure alters ethanol-induced Fos immunoreactivity and dopaminergic activity in the mesocorticolimbic pathway of the adolescent brain
(Pergamon-Elsevier Science Ltd, 2015-08)
Prenatal ethanol exposure (PEE) promotes alcohol intake during adolescence, as shown in clinical and pre-clinical animal models. The mechanisms underlying this effect of prenatal ethanol exposure on postnatal ethanol intake ...
Early exposure to environmental enrichment modulates the effects of prenatal ethanol exposure upon opioid gene expression and adolescent ethanol intake
(Pergamon-Elsevier Science Ltd, 2019-12)
Prenatal ethanol exposure (PEE) promotes ethanol consumption in the adolescent offspring accompanied by the transcriptional regulation of kappa opioid receptor (KOR) system genes. This study analysed if environmental ...
Placental Hypoxia and Foetal Development Versus Alcohol Exposure in Pregnancy
(OXFORD UNIV PRESS, 2012-04)
Aims: To examine the causes of variability in the effect of maternal drinking on the foetus, with particular reference to the pattern, frequency and duration of the period of drinking, differences in maternal, foetal and ...
Prenatal ethanol increases ethanol intake throughout adolescence, alters ethanol-mediated aversive learning, and affects μ but not δ or κ opioid receptor mRNA expression
(Wiley Blackwell Publishing, Inc, 2015-04)
Animal models of prenatal ethanol exposure (PEE) have indicated a facilitatory effect of PEE on adolescent ethanol intake, but few studies have assessed the effects of moderate PEE throughout adolescence. The mechanisms ...
Prenatal and postnatal ethanol experiences modulate consumption of the drug in rat pups, without impairment in the granular cell layer of the main olfactory bulb
(Pergamon-Elsevier Science Ltd, 2011-01-10)
The effect of moderate exposure to ethanol during late gestation was studied in terms of its interaction with moderate exposure during nursing from an intoxicated dam. A further issue was whether behavioral effects of ...
Olfactory preference for ethanol following social interaction with an intoxicated peer in adolescent rats exposed to ethanol in-uteroPreferencia por el olor del etanol tras la interacción social con un congénere intoxicado en ratas adolescentes expuestas a la droga in-útero
(Universidad de Oviedo, 2013-07)
Background: Prenatal exposure to ethanol and later socially mediated exposure predicts ethanol intake in human adolescents. Animal rat models indicate that brief interactions with an ethanol-intoxicated peer result in ...
Prenatal ethanol exposure potentiates isolation-induced ethanol consumption in young adult rats
(Elsevier Science Inc, 2019-03)
Prenatal and/or early postnatal ethanol exposure (PEE) is associated with significant behavioral and physiological deficits in offspring, including alterations in stress response systems and a greater likelihood of alcohol ...
Prenatal ethanol exposure modifies locomotor activity and induces selective changes in Met-Enkephalin content in adolescent rats
(Dougmar Group, 2019)
Prenatal ethanol exposure (PEE) facilitates alcohol acceptance and intake, suggesting that ethanol in uteromay increase the probability of drug abuse during adolescence and adulthood. Alcohol reinforcement involves the ...