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Structure-affinity relationships of halogenated predicentrine and glaucine derivatives at D1 and D2 dopaminergic receptors: Halogenation and D1 receptor selectivity
(Elsevier Ltd, 2005)
Halogenation of the aporphine alkaloid boldine at the 3-position leads to increased affinity for rat brain D1-like dopaminergic receptors with some selectivity over D2-like receptors. A series of 3-halogenated and ...
A possible structural determinant of selectivity of boldine and derivatives for the α1A-adrenoceptor subtype
(John Wiley and Sons Inc., 1996)
1 The selectivity of action of boldine and the related aporphine alkaloids, predicentrine (9-O-methylboldine) and glaucine (2,9-O-dimethylboldine) on α1-adrenoceptor subtypes was studied by examining [3H]-prazosin competition ...
Structure-affinity relationships of halogenated predicentrine and glaucine derivatives at D-1 and D-2 dopaminergic receptors: halogenation and D-1 receptor selectivity
(PERGAMON-ELSEVIER SCIENCE LTD, 2005-06-01)
Halogenation of the aporphine alkaloid boldine at the 3-position leads to increased affinity for rat brain D-1-like dopaminergic receptors with some selectivity over D-2-like receptors. A series of 3-halogenated and ...
A possible structural determinant of selectivity of boldine and derivatives for the (xlA-adrenoceptor subtype
(Stockton Press, 1996-09-09)
1 The selectivity of action of boldine and the related aporphine alkaloids, predicentrine (9-0-
methylboldine) and glaucine (2,9-0-dimethylboldine) on oel-adrenoceptor subtypes was studied by
examining [3H]-prazosin ...
Trypanocidal effect of boldine and related alkaloids upon several strains of Trypanosoma cruzi
(Elsevier Science Ltd., 1993-11-01)
The alkaloids boldine, glaucine, predicentrine, apomorphine, coclaurine, norarmepavine and codeine
were tested against the epimastigotes of the Tulahuén and LQ strains and the DM 28c clone of
Trypanosoma cruzi. The ...
A possible structural determinant of selectivity of boldine and derivatives for the al A -adrenoceptor subtype
(Stockton Press, 1996-09-19)
1 The selectivity of action of boldine and the related aporphine alkaloids, predicen trine (9-0methylboldine)
and glaucine (2,9-0-dimethylboldine) on (X¡-adrenoceptor subtypes was studied by
examining pH]-prazosin ...
Phytochemical Analysis of Alkaloids fron the Chilean Endemic Tree Cryptocarya Alba
(Sociedad Chilena Química, 2016)
A phytochemical study of the roots and aerial parts of Cryptocarya alba (Mol.) Looser (Lauraceae), an endemic Chilean tree and the southernmost Cryptocarya species, led for the first time to the isolation and unambiguous ...
Aporphine metho salts as neuronal nicotinic acetylcholine receptor blockers
(2007)
(S)-Aporphine metho salts with the 1,2,9, 10 oxygenation pattern displaced radioligands from recombinant human 0 and alpha 4 beta 2 neuronal nicotinic acetylcholine receptors (nAChR) at low micromolar concentrations. The ...
Phytochemical analysis of alkaloids from the Chilean endemic tree Cryptocarya alba
(CIENCIAS, 2016)
A phytochemical study of the roots and aerial parts of Cryptocarya alba (Mol.) Looser (Lauraceae), an endemic Chilean tree and the southernmost Cryptocarya species, led for the first time to the isolation and unambiguous ...
Metabolismo e atividades biológicas de espécies de zanthoxylum do Brasil
(Instituto de QuímicaPrograma de Pós Graduação em QuímicaIQbrasil, 2016-09-02)
Este trabalho tem como objetivo contribuir com o conhecimento fitoquímico das
espécies do gênero Zanthoxylum. O presente estudo justifica-se devido ao escasso
número de informações sobre a composição química de espécies ...