Premature thelarche is a benign condition, which has been described as a "variant of puberty". Early breast development is especially prevalent during the first year of life, when the gonadal axis is usually active. ...

Precocious puberty is defined as the development of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys. Gonadotropin-dependent precocious puberty (GDPP) results from the premature ...

Precocious thelarche is the breast development before 8 years of age with two peaks of incidence during the first two years of life and after 6 years of age. A 4.75-year-old girl presented with thelarche associated to an ...

Objective To identify GNAS1 gene mutations in girls with exaggerated and/or chronic fluctuating thelarche for at least 1-year duration with no other signs of precocious puberty, skeletal dysplasia, or typical skin lesions ...

Context: Premature adrenarche (PA) has been associated with increased metabolic risk. Objective: To describe the risk of precocious thelarche (PT; ,8 years), pubarche (PP; girls ,8 years, boys ,9 years), and gonadarche ...

Se revisa la fisiología de la maduración sexual, desde la vida intrauterina hasta la pubertad, con énfasis en los eventos que ocurren durante la pubertad tanto en la mujer como en el varón. Luego se describen las alteraciones ...

The objective of this systematic review was to evaluate the association between a soybased infant diet and the onset of puberty. We included studies in which children were fed a soy-based diet, and we compared them with ...