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Solid dispersions with hydrogenated castor oil increase solubility, dissolution rate and intestinal absorption of praziquantel
(2010-01-01)
The solubility behavior of drugs remains one of the most challenging aspects in formulation development. Solid Dispersion (SD) has tremendous potential for improving drug solubility. Although praziquantel (PZQ) is the first ...
High-performance liquid chromatography determination of praziquantel in tablets and raw materials
(2006-10-01)
A specific and sensitive high-performance liquid chromatographic method was developed for the assay of praziquantel in raw materials and tablets. It was also found that the excipients in the commercial tablet preparation ...
High-performance liquid chromatography determination of praziquantel in tablets and raw materials
(2006-10-01)
A specific and sensitive high-performance liquid chromatographic method was developed for the assay of praziquantel in raw materials and tablets. It was also found that the excipients in the commercial tablet preparation ...
Solid dispersions with hydrogenated castor oil increase solubility, dissolution rate and intestinal absorption of praziquantel
(Universidade de São Paulo, Faculdade de Ciências Farmacêuticas, 2010)
The solubility behavior of drugs remains one of the most challenging aspects in formulation development. Solid Dispersion (SD) has tremendous potential for improving drug solubility. Although praziquantel (PZQ) is the first ...
Development of praziquantel-loaded PLGA nanoparticles and evaluation of intestinal permeation by the everted gut Sac model
(Amer Scientific Publishers, 2006-09-01)
Praziquantel has been shown to be highly effective against all known species of Schistosoma infecting humans. Spherical nanoparticles made of poly(D,L-lactide-co-glycolide) acid with controlled size were designed as drug ...
Effectiveness of hyperbaric oxygen for experimental treatment of schistosomiasis mansoni using praziquantel-free and encapsulated into liposomes: Assay in adult worms and oviposition
(Elsevier B. V., 2015)
The treatment of schistosomiasis depends on a single drug: praziquantel (PZQ). However, this treatment presents limitations such as low and/or erratic bioavailability that can contribute to cases of tolerance. Improvements ...
Solid dispersions with hydrogenated castor oil increase solubility, dissolution rate and intestinal absorption of praziquantel
(Universidade de São Paulo (USP), Conjunto Quimicas, 2014)
Thermoanalytical study of praziquantel-loaded PLGA nanoparticles
(2006-10-01)
Polymeric nanoparticles have received great attention as potential controlled drug delivery systems. Biodegradable polymers has been extensively used in the development of these drug carriers, and the polyesters such as ...
La inflamación causada por el tratamiento con praziquantel depende de la localización del cisticerco de Taenia solium en la neurocisticercosis porcina
(Universidad Peruana Cayetano HerediaPE, 2016)
La neurocisticercosis (NCC) es una enfermedad pleomórfica que resulta de la infección del sistema nervioso central con cisticercos del helminto parásito Taenia solium. La inflamación alrededor del cisticerco es la principal ...