Buscar
Mostrando ítems 1-10 de 21
Postsynaptic cleft density changes with combined exercise protocols in an experimental model of muscular hypertrophy
(2021-06-01)
The vertical ladder-based protocols contribute to the NMJ junction's adaptations, and when combined with and without load, can be potentiated. The present study aimed to investigate postsynaptic regions of the biceps brachii ...
A new tool to sense pH changes at the neuromuscular junction synaptic cleft
(Nature, 2020-11-24)
Synaptic transmission triggers transient acidification of the synaptic cleft. Recently, it has been shown that pH affects the opening of postsynaptic channels and therefore the production of tools that allow to study these ...
Adaptações na junção neuromuscular de ratos Wistar submetidos ao alongamento estático e exercício resistido: análises morfológicas, moleculares e funcionais
(Universidade Estadual Paulista (Unesp), 2021-05-26)
Este trabalho busca descrever as diversas adaptações no ventre muscular e na região pós-sináptica da junção neuromuscular (JNM) frente ao alongamento estático prévio e a sua combinação ou não com as diferentes modalidades ...
Análises morfoquantitativas de avaliação da junção neuromuscular
(Universidade Estadual Paulista (Unesp), 2022-11-09)
A Junção Neuromuscular (JNM) é a região entre o terminal axonal e a fibra muscular,
gerando respostas mecânicas, como a contração muscular. Constituída pela região
pré-sináptica, fenda sináptica e a região pós-sináptica ...
Direct effects of ethanol on neuronal differentiation: An in vitro analysis of viability and morphology
(Pergamon-Elsevier Science Ltd, 2016-10)
The deleterious effects of ethanol (EtOH) on the brain have been widely described, but its effects on theneuronal cytoskeleton during differentiation have not yet been firmly established. In this context, ouraim was to ...
Modulation of acid sensing ion channel dependent protonergic neurotransmission at the mouse calyx of Held
(Pergamon-Elsevier Science Ltd, 2020-07)
Acid-sensing ion channels (ASICs) regulate synaptic activities and play important roles in neurodegenerative diseases. It has been reported that homomeric ASIC-1a channels are expressed in neurons of the medial nucleus of ...
Acid-Sensing Ion Channels Activated by Evoked Released Protons Modulate Synaptic Transmission at the Mouse Calyx of Held Synapse
(Society for Neuroscience, 2017-03)
Acid-sensing ion channels (ASICs) regulate synaptic activities and play important roles in neurodegenerative diseases. We found that these channels can be activated in neurons of the medial nucleus of the trapezoid body ...
Avaliação comportamental e morfofuncional de junções neuromusculares e músculos estriados esqueléticos de camundongos com disfunção colinérgica a longo prazo
(Universidade Federal de Minas GeraisUFMG, 2015-03-02)
The Neuromuscular Junctions (NMJ) is essential for the neuronal communication between the nerve terminals and muscle fibers leading to muscle contraction. One of the most critical processes of cholinergic transmission ...
GABAB receptors in neuroendocrine regulation
(Springer, 2008-09)
Gamma-amino butyric acid (GABA), in addition to being a metabolic intermediate and the main inhibitory neurotransmitter in the synaptic cleft, is postulated as a neurohormone, a paracrine signaling molecule, and a trophic ...