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Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences
(BioMed Central, 2016-06-30)
Population differentiation has proved to be effective for identifying loci under geographically localized positive selection, and has the potential to identify loci subject to balancing selection. We have previously ...
Potential ligand-binding residues in rat olfactory receptors identified by correlated mutation analysis
(Harwood Acad Publ Gmbh, 1995-01-01)
A family of G-protein-coupled receptors is believed to mediate the recognition of odor molecules. In order to identify potential ligand-binding residues, we have applied correlated mutation analysis to receptor sequences ...
The Cap gene of porcine circovirus type 2 (PCV2) evolves by positive selection in vitro
(São Paulo, 2010)
This article reports the genetic divergence of PCV2 after passages in VERO and SK-RST cell lines. Fisher's exact test indicated a trend for positive selection on the cap gene. These results allow insights on the development ...
Adaptive positive selection for keystroke dynamics
(SpringerDordrecht, 2015-12)
Current technologies provide state of the art services but, at the same time, increase data exposure, mainly due to Internet-based applications. In view of this scenario, improved authentication mechanisms are needed. ...
Bird-mediated selection on fruit display traits in Celtis ehrenbergiana (Cannabaceae)
(Evolutionary Ecology Ltd, 2014-08)
Background: In mutualistic interactions of fleshy-fruited plants and seed-dispersing birds, dispersers act as natural selection agents on fruit display traits. Bird-mediated phenotypic selection on maternal and seed level ...
Molecular evolution of a malaria resistance gene (DARC) in primates
(SPRINGERNEW YORK, 2012)
Genes involved in host-pathogen interactions are often strongly affected by positive natural selection. The Duffy antigen, coded by the Duffy antigen receptor for chemokines (DARC) gene, serves as a receptor for Plasmodium ...
Genomic data as the hitchhiker's guide to cattle adaptation: tracking the milestones of past selection in the bovine genome
(Frontiers In Genetics, 2015)
The bovine species have witnessed and played a major role in the drastic socio-economical changes that shaped our culture over the last 10,000 years. During this journey, cattle hitchhiked on human development and colonized ...
Contrasting patterns of selection between MHC I and II across populations of Humboldt and Magellanic penguins
(Wiley, 2016)
The evolutionary and adaptive potential of populations or species facing an emerging infectious disease depends on their genetic diversity in genes, such as the major histocompatibility complex (MHC). In birds, MHC class ...