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Structural insights into the oligomerization and architecture of eukaryotic membrane pore-forming toxins
(Elsevier, 2011-02)
Pore-forming toxins (PFTs) are proteins that are secreted as soluble molecules and are inserted into membranes to form oligomeric transmembrane pores. In this paper, we report the crystal structure of Fragaceatoxin C (FraC), ...
Ceramic Material Porous Structure Prepared Using Pore-Forming Additives
(Springer, 2017-05)
Porous ceramic materials exhibit high permeability, specific surface, and thermal shock resistance, and therefore they may be used successfully in the production of filters, membranes, and as a substrate for catalytic ...
P2X7R large pore is partially blocked by pore forming proteins antagonists in astrocytes
(Springer Verlag, 2016)
The membranotropic activity of N-terminal peptides from the pore-forming proteins sticholysin I and II is modulated by hydrophobic and electrostatic interactions as well as lipid composition
(Indian Acad Sciences, 2011-12-01)
The sea anemone Stichodactyla helianthus produces two pore-forming proteins, sticholysins I and II (St I and St II). Despite their high identity (93%), these toxins exhibit differences in hemolytic activity that can be ...
Model peptides mimic the structure and function of the N-terminus of the pore-forming toxin sticholysin II
(Wiley-Blackwell, 2006-01-01)
To investigate the role of the N-terminal region in the lytic mechanism of the pore-forming toxin sticholysin II (St II), we studied the conformational and functional properties of peptides encompassing the first 30 residues ...
Model peptides mimic the structure and function of the N-terminus of the pore-forming toxin sticholysin II
(Wiley-Blackwell, 2006-01-01)
To investigate the role of the N-terminal region in the lytic mechanism of the pore-forming toxin sticholysin II (St II), we studied the conformational and functional properties of peptides encompassing the first 30 residues ...
Validation of a mutant of the pore-forming toxin sticholysin-I for the construction of proteinase-activated immunotoxins
(Oxford University Press, 2011-06-01)
The use of pore-forming toxins from sea anemones (actinoporins) in the construction of immunotoxins (ITs) against tumour cells is an alternative for cancer therapy. However, the main disadvantage of actinoporin-based ITs ...
Validation of a mutant of the pore-forming toxin sticholysin-I for the construction of proteinase-activated immunotoxins
(Oxford University Press, 2011-06-01)
The use of pore-forming toxins from sea anemones (actinoporins) in the construction of immunotoxins (ITs) against tumour cells is an alternative for cancer therapy. However, the main disadvantage of actinoporin-based ITs ...
P2X7R large pore is partially blocked by pore forming proteins antagonists in astrocytes
(Springer Verlag, 2016)