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Polyhydroxylated sulfated steroids derived from 5α-cholestanes as antiviral agents against herpes simplex virus
(Springer Wien, 2016-07)
Twelve polyhydroxylated sulfated steroids synthesized from a 5α-cholestane skeleton with different substitutions in C-2, C-3 and C-6 were evaluated for cytotoxicity and antiviral activity against herpes simplex virus (HSV) ...
Synthesis and acetylcholinesterase inhibitory activity of polyhydroxylated sulfated steroids: structure/activity studies
(Elsevier, 2013-08)
Disulfated and trisulfated steroids have been synthesized from cholesterol and their acetylcholinesterase inhibitory activity has been evaluated. In our studies we have found that the activity was not only dependent on the ...
Minutosides A and B, antifungal sulfated steroid xylosides from the patagonian starfish Anasterias minuta
(American Chemical Society, 2005-08)
Two new sulfated polyhydroxylated steroidal xylosides, minutosides A (1) and B (2), together with the known pycnopodioside B (3), have been isolated from the brine shrimp active fraction of the ethanolic extract of the ...
Synthesis and cytotoxic evaluation of four new 6E-hydroximinosteroids
(Elsevier, 2014-03-13)
Four new 6E-hydroximinosteroids (1, 2a, 3 and 4) have been synthesized from the corresponding ketones, 2β,3β-dihydroxy-5α-cholestan-6-one (5), 2α,3α-dihydroxy-5α-cholestan-6-one (6), 2β,3α-dihydroxy-5α-cholestan-6-one (7) ...
Secondary Metabolites of Biological Significance from Echinoderms
(CRC Press - Taylor & Francis Group, 2014)
The extraordinary development of marine natural products chemistry during the last three decades has been prompted by the fact that marine organisms are sources of new natural products with unusual structural features that ...