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Characterization of the rat exploratory behavior in the elevated plus-maze with Markov chains
(ELSEVIER SCIENCE BV, 2010)
The elevated plus-maze is an animal model of anxiety used to study the effect of different drugs on the behavior of the animal It consists of a plus-shaped maze with two open and two closed arms elevated 50 cm from the ...
Similar anxiolytic-like effects following intra-amygdala infusions of benzodiazepine receptor agonist and antagonist: Evidence for the release of an endogenous benzodiazepine inverse agonist in mice exposed to elevated plus-maze test
(Elsevier B.V., 2009-04-24)
Previous studies have demonstrated that microinjections of midazolam, a benzodiazepine receptor agonist, into the amygdala produce anxiolytic-like effects in elevated plus-maze (EPM)-naive rodents. However, systemic or ...
Similar anxiolytic-like effects following intra-amygdala infusions of benzodiazepine receptor agonist and antagonist: Evidence for the release of an endogenous benzodiazepine inverse agonist in mice exposed to elevated plus-maze test
(Elsevier B.V., 2009-04-24)
Previous studies have demonstrated that microinjections of midazolam, a benzodiazepine receptor agonist, into the amygdala produce anxiolytic-like effects in elevated plus-maze (EPM)-naive rodents. However, systemic or ...
Characterization of rat behavior in the elevated plus-maze using a directed graph
(ELSEVIER SCIENCE BV, 2009)
The elevated plus-maze is a device widely used to assess rodent anxiety under the effect of several treatments, including pharmacological agents. The animal is placed at the center of the apparatus, which consists of two ...
THE EFFECT of CORTICOSTERONE in RATS SUBMITTED TO the ELEVATED PLUS-MAZE and TO PENTYLENETETRAZOL-INDUCED CONVULSIONS
(Elsevier B.V., 1994-12-01)
1. in order to examine the effects of corticosterone in the anxiety response, the effect of acute, subchronic and chronic corticosterone (CORT) administration were studied using two animal models to study using two animal ...
Social separation and diazepam withdrawal increase anxiety in the elevated plus-maze and serotonin turnover in the median raphe and hippocampus
(SAGE PUBLICATIONS LTD, 2010)
The present work aimed to evaluate the effects of social separation for 14 days (chronic stress) and of withdrawal from a 14-day treatment with diazepam (acute stress) on the exploratory behaviour of male rats in the ...
Social separation and diazepam withdrawal increase anxiety in the elevated plus-maze and serotonin turnover in the median raphe and hippocampus
(Sage Publications Ltd, 2010-05-01)
The present work aimed to evaluate the effects of social separation for 14 days (chronic stress) and of withdrawal from a 14-day treatment with diazepam (acute stress) on the exploratory behaviour of male rats in the ...
Social separation and diazepam withdrawal increase anxiety in the elevated plus-maze and serotonin turnover in the median raphe and hippocampus
(Sage Publications Ltd, 2010-05-01)
The present work aimed to evaluate the effects of social separation for 14 days (chronic stress) and of withdrawal from a 14-day treatment with diazepam (acute stress) on the exploratory behaviour of male rats in the ...
Longitudinal study of daily variation of rats' behavior in the elevated plus-maze
(Elsevier B.V., 2003-01-01)
We conducted a longitudinal study about daily variation of Wistar male rats' behavior in the elevated plus-maze (EPM) evaluated in the 1st, 2nd, 3rd, 6th, 12th, and 18th months of life. Animals were submitted to the plus-maze ...
Simulation of behavioral profiles in the plus-maze: A Classification and Regression Tree approach
(2013-07-25)
This article introduces a simulation model of rat behavior in the elevated plus-maze, designed through a Decision trees approach using Classification and Regression algorithms. Starting from the analysis of the behavior ...