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Pleiotropic genes affecting carcass traits in bos indicus (Nellore) cattle are modulators of growth
(2016-07-01)
Two complementary methods, namely Multi-Trait Meta-Analysis and Versatile Gene-Based Test for Genome-wide Association Studies (VEGAS), were used to identify putative pleiotropic genes affecting carcass traits in Bos indicus ...
Actors with Multiple Roles: Pleiotropic Enhancers and the Paradigm of Enhancer Modularity
(Elsevier Science London, 2019-06)
The current paradigm in the field of gene regulation postulates that regulatory information for generating gene expression is organized into modules (enhancers), each containing the information for driving gene expression ...
The pleiotropic transcriptional regulator NlpR contributes to the modulation of nitrogen metabolism, lipogenesis and triacylglycerol accumulation in oleaginous rhodococci
(Wiley Blackwell Publishing, Inc, 2017-01-25)
The regulatory mechanisms involved in lipogenesis and triacylglycerol (TAG) accumulation are largely unknown in oleaginous rhodococci. In this study a regulatory protein (here called NlpR: Nitrogen lipid Regulator), which ...
Natural Antimicrobial Peptides: Pleiotropic Molecules in Host Defense
(Scientific Research, 2013-12)
Natural antimicrobial peptides (AMPs) are small cationic molecules that display antimicrobial activity against a wide range of bacteria, fungi and viruses. AMPs are multifunctional molecules that have an essential activity ...
Fimbria-encoding Gene Yadc Has A Pleiotropic Effect On Several Biological Characteristics And Plays A Role In Avian Pathogenic Escherichia Coli Pathogenicity
(AMER SOC MICROBIOLOGYWASHINGTON, 2016)
Allatotropin: A pleiotropic neuropeptide that elicits mosquito immune responses
(Public Library of Science, 2017-04)
Allatotropins (AT) are neuropeptides with pleotropic functions on a variety of insect tissues. They affect processes such as juvenile hormone biosynthesis, cardiac rhythm, oviduct and hindgut contractions, nutrient absorption ...
Enhanced phosphatidylinositol 3-kinase (PI3K)/Akt signaling has pleiotropic targets in hippocampal neurons exposed to iron-induced oxidative stress
(American Society For Biochemistry And Molecular Biology, 2013-05)
The phosphatidylinositol 3-kinase (PI3K)/Akt pathway is a key component in synaptic plasticity and neuronal survival. The aim of this work was to investigate the participation of the PI3K/Akt pathway and its outcome ...