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The fate of plasma kallikrein in normal and kininogen-deficient rats
(Swets Zeitlinger Publishers, 1998-02-01)
The clearance of exogenous plasma kallikrein, its uptake by liver, spleen, kidneys, lungs and its extravasation in the paws were determined in normal Wistar rats, normal and kininogen-deficient Brown Norway rats. Kallikrein ...
PLASMA, KALLIKREIN CLEARANCE BY THE LIVER - A REVIEW
(Assoc Bras Divulg Cientifica, 1994-08-01)
1. The liver is the main organ clearing both plasma and tissue kallikreins from the circulation. Hepatocytes are responsible for the internalization of rat plasma kallikrein (RPK) and the clearance of plasma kallikrein by ...
Studies on the activation of the pre-kininogenin-kininogenin (pre-kallikrein-kallikrein) system by sulfated polysaccharides and kaolin
(1979-12-01)
The activation of pre-kininogenin to kininogenin (pre-kallikrein to kallikrein) is one of the steps in the series of reactions of a complex system, linked also to fibrinolysis and coagulation, that leads to kinin release ...
Studies on the activation of the pre-kininogenin-kininogenin (pre-kallikrein-kallikrein) system by sulfated polysaccharides and kaolin
(1979-12-01)
The activation of pre-kininogenin to kininogenin (pre-kallikrein to kallikrein) is one of the steps in the series of reactions of a complex system, linked also to fibrinolysis and coagulation, that leads to kinin release ...
COMPARISON BETWEEN CLEARANCE RATES of PLASMA KALLIKREIN and of PLASMA KALLIKREIN-ALPHA-MACROGLOBULIN COMPLEXES BY the LIVER
(Elsevier B.V., 1993-07-01)
1. Alpha-Macroglobulins (alphaMs) were isolated from the serum of injured rats through a two-stage method: gel filtration and ultracentrifugation.2. the clearance rates of rat plasma kallikrein (RPK) and alphaMs-RPK complexes ...
Glycosaminoglycans affect the interaction of human plasma kallikrein with plasminogen, factor XII and inhibitors
(Associação Brasileira de Divulgação Científica, 2003-08-01)
Human plasma kallikrein, a serine proteinase, plays a key role in intrinsic blood clotting, in the kallikrein-kinin system, and in fibrinolysis. The proteolytic enzymes involved in these processes are usually controlled ...
Pharmacological characterization of novel tissue kallikrein inhibitors in vivo
(Elsevier B.V., 1996-05-01)
In this study we have investigated the effect of novel tissue kallikreins on the plasma protein exudation induced by porcine pancreatic kallikrein (PPK) in the rabbit skin in vivo. the tissue kallikrein inhibitors here ...