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Progressive uterine artery occlusion in the Guinea pig leads to defects in placental structure that relate to fetal growth
(W.B. Saunders Ltd, 2018)
© 2018 Elsevier Ltd Intrauterine growth restriction (IUGR) is a common obstetric complication with immediate and life-long consequences for offspring health. Yet the mechanisms underlying its aetiology require elucidation. ...
Altered Glycosylation Contributes to Placental Dysfunction Upon Early Disruption of the NK Cell-DC Dynamics
(Frontiers Media, 2020-07)
Immune cells [e. g., dendritic cells (DC) and natural killer (NK) cells] are critical players during the pre-placentation stage for successful mammalian pregnancy. Proper placental and fetal development relies on balanced ...
Sex Steroids Modulate Uterine-Placental Vasculature: Implications for Obstetrics and Neonatal Outcomes
(Frontiers Media, 2016)
Adequate blood supply to the uterine-placental region is crucial to ensure the transport of oxygen and nutrients to the growing fetus. Multiple factors intervene to achieve appropriate uterine blood flow and the structuring ...
Does obesity in pregnancy related to fetal death due to placental insufficiency? Se relaciona la obesidad en el embarazo con muerte fetal por insuficiencia placentaria
(Sociedad Chilena de Obstetricia y Ginecologia, 2017)
We present 4 cases of fetal death in obese pregnant women with term pregnancies, with several placental findings suggesting placental insufficiency, that could be associated with obesity. According to recent evidence obesity ...
Periodontitis and placental growth factor in oral fluids are early pregnancy predictors of gestational diabetes mellitus
(Wiley-Blackwell, 2018)
© 2018 American Academy of Periodontology. Background: Gestational diabetes mellitus (GDM) affects around 7% to 10% of all pregnancies. Early detection of predisposition to GDM is the first step in developing efficacious ...
Maternal testosterone and placental function: Effect of electroacupuncture on placental expression of angiogenic markers and fetal growth
(Elsevier, 2016)
Women with polycystic ovary syndrome (PCOS) have elevated circulating androgens during pregnancy and are at an increased risk of adverse pregnancy outcomes. Here we tested the hypotheses that maternal androgen excess ...
Maternal overweight induced by a diet with high content of saturated fat activates placental mTOR and eIF2α signaling and increases fetal growth in rats.
(Society For The Study Of Reproduction, 2013-09)
The mammalian target of rapamycin (mTOR) and the eukaryotic initiation factor 2 (eIF2) signaling pathways control protein synthesis in response to nutrient availability. Moreover mTOR is a positive regulator of placental ...