Buscar
Mostrando ítems 1-10 de 230
Estrogen effects on pilocarpine-induced temporal lobe epilepsy in rats
(ELSEVIER IRELAND LTD, 2009)
Objetive: To evaluate the effects of conjugated equine estrogens (CEE) on the pilocarpine-induced epilepsy in rats. Study design: 40 female rats were divided into: GPC (positive control) presented ""status epilepticus"" ...
Reactive oxygen species generated by NADPH oxidase are involved in neurodegeneration in the pilocarpine model of temporal lobe epilepsy
(ELSEVIER IRELAND LTD, 2010)
Reactive oxygen species (ROS) appear to be involved in several neurodegenerative disorders. We tested the hypothesis that oxidative stress could have a role in the hippocampal neurodegeneration observed in temporal lobe ...
Tyrosine phosphorylation is increased in the rat hippocampus during the status epilepticus induced by pilocarpine
(Elsevier B.V., 1998-09-01)
Phosphorylation of tyrosine residue in proteins is an important modulatory process for membrane transduction and cell signaling and for several cellular functions. the concentration and distribution of phosphotyrosine ...
The course of untreated seizures in the pilocarpine model of epilepsy
(Elsevier B.V., 1999-04-01)
The course of untreated epilepsy is not well. established. This study uses a model of chronic limbic epilepsy (pilocarpine model of epilepsy) to determine the pattern of occurrence of seizures in untreated animals. Following ...
Expression of vitamin D receptor mRNA in the hippocampal formation of rats submitted to a model of temporal lobe epilepsy induced by pilocarpine
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Vitamin D (VD), is a steroid hormone with multiple functions in the central nervous system (CNS), producing numerous physiological effects mediated by its receptor (VDR). Clinical and experimental studies have shown a link ...
The sleep-wake cycle in adult rats following pilocarpine-induced temporal lobe epilepsy
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2010)
The relationship between sleep and epilepsy is both complex and clinically significant. Temporal lobe epilepsy (TLE) influences sleep architecture, while sleep plays an important role in facilitating and/or inhibiting ...
Glucose utilization during interictal intervals in an epilepsy model induced by pilocarpine: A qualitative study
(Lippincott Williams & Wilkins, 1998-10-01)
Purpose: Interictal intervals in pilocarpine-induced chronic epilepsy are characterized by apparent normal electrographic activity and longer sleep periods or drowsiness or both. Sparse information exists concerning the ...
CIRCUIT MECHANISMS of SEIZURES in the PILOCARPINE MODEL of CHRONIC EPILEPSY - CELL LOSS and MOSSY FIBER SPROUTING
(Lippincott-raven Publ, 1993-11-01)
We used the pilocarpine model of chronic spontaneous recurrent seizures to evaluate the time course of supragranular dentate sprouting and to assess the relation between several changes that occur in epileptic tissue with ...
Long-Term Effects of Anterior Thalamic Nucleus Deep Brain Stimulation on Spatial Learning in the Pilocarpine Model of Temporal Lobe Epilepsy
(Wiley, 2018)
Introduction and ObjectivesCognitive impairment is a significant comorbidity of temporal lobe epilepsy that is associated with extensive hippocampal cell loss. Deep brain stimulation (DBS) of the anterior thalamic nucleus ...