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Botanical drug clinical trial: common issues and future options
Botanical drugs are plant-derived, complex mixtures which may have synergistic effects.
In order to understand this disparity between human use and drugs approved by regulatory agencies,
we analyzed botanical drug clinical ...
Predictive Value of Phase I Trials for Safety in Later Trials and Final Approved Dose: Analysis of 61 Approved Cancer Drugs
(Amer Assoc Cancer ResearchPhiladelphiaEUA, 2014)
Motivation and frustration in cardiology trial participation: the patient perspective
(Faculdade de Medicina / USP, 2012)
OBJECTIVE: The participation of humans in clinical cardiology trials remains essential, but little is known regarding participant perceptions of such studies. We examined the factors that motivated participation in such ...
Motivation and frustration in cardiology trial participation: The patient perspective
(Universidade de São Paulo (USP), Hospital das Clínicas, 2012-01-01)
OBJECTIVE: The participation of humans in clinical cardiology trials remains essential, but little is known regarding participant perceptions of such studies. We examined the factors that motivated participation in such ...
Motivation and frustration in cardiology trial participation: The patient perspective
(Universidade de São Paulo (USP), Hospital das Clínicas, 2012-01-01)
OBJECTIVE: The participation of humans in clinical cardiology trials remains essential, but little is known regarding participant perceptions of such studies. We examined the factors that motivated participation in such ...
A molecular biology and phase II trial of lapatinib in children with refractory CNS malignancies: a pediatric brain tumor consortium study.
(Springer, 2013-07)
High expression of ERBB2 has been reported in medulloblastoma and ependymoma; EGFR is amplified and over-expressed in brainstem glioma suggesting these proteins as potential therapeutic targets. We conducted a molecular ...
Os critérios da indústria farmacêutica no direcionamento dos ensaios clínicos: o que aumentaria a participação do Brasil?
(2022)
Os ensaios clínicos representam uma ferramenta essencial de geração de conhecimento e inovação para a indústria farmacêutica. Apesar de o Brasil ser o 7º maior mercado para a indústria e apresentar uma demografia diversa ...
Disulfiram repurposing in the combined chemotherapy of Chagas disease A protocol for phase I/II clinical trial
(Medicine Case Reports and Study Protocol, 2021)