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ArrayPitope: Automated analysis of amino acid substitutions for peptide microarray-based antibody epitope mapping
(Public Library of Science, 2017-01)
Identification of epitopes targeted by antibodies (B cell epitopes) is of critical importance for the development of many diagnostic and therapeutic tools. For clinical usage, such epitopes must be extensively characterized ...
Towards High-throughput Immunomics for Infectious Diseases: Use of Next-generation Peptide Microarrays for Rapid Discovery and Mapping of Antigenic Determinants
(American Society for Biochemistry and Molecular Biology, 2015-04)
Complete characterization of antibody specificities associated to natural infections is expected to provide a rich source of serologic biomarkers with potential applications in molecular diagnosis, follow-up of chemotherapeutic ...
Elapid Snake Venom Analyses Show the Specificity of the Peptide Composition at the Level of Genera Naja and Notechis
(Mdpi Ag, 2014-03-01)
Elapid snake venom is a highly valuable, but till now mainly unexplored, source of pharmacologically important peptides. We analyzed the peptide fractions with molecular masses up to 10 kDa of two elapid snake venoms-that ...
HLA Class II Specificity Assessed by High-Density Peptide Microarray Interactions
(American Association of Immunologists, 2020-06)
The ability to predict and/or identify MHC binding peptides is an essential component of T cell epitope discovery, something that ultimately should benefit the development of vaccines and immunotherapies. In particular, ...
Identification of continuous interaction sites in PLA(2)-based protein complexes by peptide arrays
(Elsevier France-editions Scientifiques Medicales Elsevier, 2009-11-01)
Crotoxin (CA.CB) is a beta-neurotoxin from Crotalus durissus terrificus snake venom that is responsible for main envenomation effects upon biting by this snake. It is a heterodimer of an acidic protein (CA) devoid of any ...