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The effects of the C-terminal amidation of mastoparans on their biological actions and interactions with membrane-mimetic systems
(Elsevier B.V., 2014-10-01)
Polycationic peptides may present their C-termini in either amidated or acidic form; however, the effects of these conformations on the mechanisms of interaction with the membranes in general were not properly investigated ...
Monitoring the positioning of short polycationic peptides in model lipid bilayers by combining hydrogen/deuterium exchange and electrospray ionization mass spectrometry
(Elsevier B.V., 2008-12-01)
Electrospray ionization mass spectrometry (ESI-MS) was used to analyze the hydrogen/deuterium exchange properties of the mastoparan peptide Apoica-MP during interactions with lipid vesicle membranes. Synthetic peptide was ...
Monitoring the positioning of short polycationic peptides in model lipid bilayers by combining hydrogen/deuterium exchange and electrospray ionization mass spectrometry
(Elsevier B.V., 2008-12-01)
Electrospray ionization mass spectrometry (ESI-MS) was used to analyze the hydrogen/deuterium exchange properties of the mastoparan peptide Apoica-MP during interactions with lipid vesicle membranes. Synthetic peptide was ...
Study of the antimicrobial peptide indolicidin and mutants in eukaryotic modelled membrane by molecular dynamics simulations
(TAYLOR & FRANCIS LTD, 2011)
In this work the interaction of the antimicrobial peptide indolicidin (IND) and its mutants CP10A and CP11 with a eukaryotic membrane model was examined by molecular dynamics simulations. The aim was to analyse the behaviour ...
Molecular interactions of an ornithine-rich pH-responsive self-Assembling peptide with a model lipid membrane: Conformational aspects
(2016-09-01)
Investigating interactions of designed peptide-based biomaterials with lipid membranes is important for applications in nanobiotechnology. Here the interaction of an ornithine-rich pH-responsive peptide called P11-5 with ...
The lipid composition of a cell membrane modulates the interaction of an antiparasitic peptide at the air-water interface
(Elsevier B.V., 2011-07-01)
The antiparasitic property of peptides is believed to be associated with their interactions with the protozoan membrane, which calls for research on the identification of membrane sites capable of peptide binding. In this ...
Reversing the peptide sequence impacts on molecular surface behaviour
(Elsevier Science, 2016-03)
The protein's primary structure has all the information for specific protein/peptide folding and, in many cases, can define specific amphiphilic regions along molecules that are important for interaction with membranes. ...
Biophysical Studies of TOAC Analogs of the Ctx(Ile21)-Ha Antimicrobial Peptide Using Liposomes
(2022-06-01)
Antimicrobial peptides (AMP) are innate components of the defense system of many forms of life, composing the first line of defense from invading pathogens. Among many AMPs described in several databases, the Ctx(Ile21)-Ha ...
Lipid-packing perturbation of model membranes by pH-responsive antimicrobial peptides
(2017-10-01)
The indiscriminate use of conventional antibiotics is leading to an increase in the number of resistant bacterial strains, motivating the search for new compounds to overcome this challenging problem. Antimicrobial peptides, ...
On the role of surrounding regions in the fusion peptide in dengue virus infection
(2021-05-01)
Dengue virus infection depends on its fusion with the host membrane, where the binding occurs through interaction between proteins on the virus cell surface and specific viral receptors on target membranes. This process ...