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IL28B polymorphisms associated with therapy response in Chilean chronic hepatitis C patients
(2011)
AIM: To analyze the association of three IL28B single nucleotide polymorphisms with response to therapy in Chilean patients infected with hepatitis C virus (HCV)). METHODS: We studied two groups of patients with chronic ...
Quasispecies of hepatitis C virus genotype 1 and treatment outcome with Peginterferon and Ribavirin
(Elsevier B.V., 2009-07-01)
The majority of patients with chronic hepatitis C fail to respond to antiviral therapy. The genetic basis of this resistance is unknown. The quasispecies nature of HCV may have an important implication concerning viral ...
Quasispecies of hepatitis C virus genotype 1 and treatment outcome with Peginterferon and Ribavirin
(Elsevier B.V., 2009-07-01)
The majority of patients with chronic hepatitis C fail to respond to antiviral therapy. The genetic basis of this resistance is unknown. The quasispecies nature of HCV may have an important implication concerning viral ...
Induction pegylated interferon Alfa-2a and high dose ribavirin do not increase SVR in heavy patients with HCV genotype 1 and high viral loads
(2010-12-01)
Background & Aims Patients infected with hepatitis C virus (HCV) genotype 1, body weight <85 kg, and high baseline viral load respond poorly to standard doses of pegylated interferon (peginterferon) and ribavirin. We ...
Retreatment of hepatitis C patients with pegylated interferon combined with ribavirin in non-responders to interferon plus ribavirin. Is it different in real life?
(Biomed Central LtdLondonInglaterra, 2010)
Variations at multiple genes improve interleukin 28B genotype predictive capacity for response to therapy against hepatitis C infection
(Lippincott, Williams & Wilkins, 2013-11-13)
To identify genetic factors that predict sustained virological response (SVR) to pegylated interferon (Peg-IFN)/ribavirin (RBV) in HIV/hepatitis C virus (HCV) genotype 1 or 4-coinfected patients and that enhance the ...
Psychosis during peginterferon-alpha2a and ribavirin therapy: case report
(Brazilian Society of Infectious Diseases, 2006-12-01)
Pegylated Interferon-alpha, combined with ribavirin, gives high sustained virological response in patients with hepatitis C virus, an important public health problem and one of the most frequent chronic infectious diseases ...