In addition to surgery, local tumor control in pediatric oncology requires new treatments as an alternative to radiotherapy. SN-38 is an anticancer drug with proved activity against several pediatric solid tumors including ...

Pediatric solid tumors represent a distinct set of malignancies of embryonal origin whose incidence peaks in the first years of life. Specific genetic anomalies with pathogenic significance, which have helped to define the ...

Central nervous system (CNS) tumors are the most common type of solid tumors in the pediatric population. Neuroimaging is the sine quo non for state-of-the-art care of pediatric patients with central nervous system neoplasms. ...

Introduction: Collaborative clinical trials have enlarged the knowledge base about pediatric tumors; however, this is not the case for rare tumors (RT).Objective: To describe the prevalence, clinical characteristics, and ...