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The advances of Deep Brain Stimulation (DBS) for treatment of Parkinson's Disease (PD)
(HCPA/FAMED/UFRGS, 2019)
Polygenic risk prediction and SNCA haplotype analysis in a Latino Parkinson's disease cohort
(Elsevier, 2022)
Background: Large-scale Parkinson's disease (PD) genome-wide association studies (GWAS) have, until recently, only been conducted on subjects with European-ancestry. Consequently, polygenic risk scores (PRS) constructed ...
Disease severity affects obstacle crossing in people with Parkinson's disease
(Elsevier B.V., 2014-05-01)
The current study evaluated the effects of disease severity on the control of obstacle crossing in people with idiopathic Parkinson's disease (PD). Forty-five subjects participated in the study, including 15 patients with ...
Ativa Parkinson: benefícios da atividade física na qualidade de vida de pessoas com doença de Parkinson
(Universidade Estadual Paulista (Unesp), 2015-09-18)
Parkinson's disease (PD) is characterized from the dysfunction or death of dopamine-generating cells. Physical activity is used in the treatment of people with PD combined with dopaminergic medication treatment to improve ...
Parkinson's disease severity and motor subtype influence physical capacity components
(2013-01-01)
The severity of Parkinson's disease (PD) and PD's motor subtypes influence the components of physical capacity. The aim of this study was to investigate the impact of both PD severity and motor subtype in the performance ...
Variable frequency of LRRK2 variants in the Latin American research consortium on the genetics of Parkinson's disease (LARGE-PD), a case of ancestry
(Springer, 2017)
Mutations in Leucine-Rich Repeat Kinase 2 (LRRK2), primarily located in codons G2019 and R1441, represent the most common genetic cause of Parkinson's disease in European-derived populations. However, little is known about ...
An ERcentric view of Parkinson's disease
(2013)
Parkinson's disease (PD) is the second most common neurodegenerative disease and is characterized by the selective loss of dopaminergic neurons of the substantia nigra pars compacta and the accumulation of intracellular ...
An ERcentric view of Parkinson's disease
(Elsevier, 2013-03)
Parkinson's disease (PD) is the second most common neurodegenerative disease and is characterized by the selective loss of dopaminergic neurons of the substantia nigra pars compacta and the accumulation of intracellular ...
Quality of life (QoL) in relation to disease severity in Brazilian Parkinson's patients as measured using the WHOQOL-BREF
(Elsevier B.V., 2008-03-01)
This study aimed at evaluating and describing the QoL and its association with the severity of disease among Brazilian Parkinson's disease (PD) patients. In this cross-sectional study 68 PD patients were interviewed using ...
Quality of life (QoL) in relation to disease severity in Brazilian Parkinson's patients as measured using the WHOQOL-BREF
(Elsevier B.V., 2008-03-01)
This study aimed at evaluating and describing the QoL and its association with the severity of disease among Brazilian Parkinson's disease (PD) patients. In this cross-sectional study 68 PD patients were interviewed using ...