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The minicircular and extremely heteroplasmic mitogenome of the holoparasitic plant Rhopalocnemis phalloides
(Cell Press, 2021-12)
The plastid and nuclear genomes of parasitic plants exhibit deeply altered architectures,1–13 whereas the few examined mitogenomes range from deeply altered to conventional.14–20 To provide further insight on mitogenome ...
Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites
(Public Library of Science, 2019)
Malaria is caused by Plasmodium parasites, which invade and replicate in erythrocytes. For Plasmodium falciparum, the major cause of severe malaria in humans, a heterotrimeric complex comprised of the secreted parasite ...
A novel Trypanosoma cruzi protein associated to the flagellar pocket of replicative stages and involved in parasite growth
(Public Library of Science, 2015-06)
The flagellar pocket constitutes an active and strategic site in the body of trypanosomatids (i.e. parasitic protozoa that cause important human and/or livestock diseases), which participates in several important processes ...
A Flap Endonuclease (TcFEN1) Is Involved in Trypanosoma cruzi Cell Proliferation, DNA Repair, and Parasite Survival
(Wiley, 2017)
FLAP endonucleases (FEN) are involved both in DNA replication and repair by processing DNA intermediaries presenting a nucleotide flap using its phosphodiesterase activity. In spite of these important functions in DNA ...