Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the best therapeutic options to treat pain. Their use in combination with other drugs may broaden their applicability in analgesia if their ceiling and adverse effects ...

P>Cholinergic agonists and acetylcholinesterase inhibitors, such as neostigmine, produce a muscarinic receptor-mediated antinociception in several animal species that depends on activation of spinal cholinergic neurons. ...

BACKGROUND AND OBJECTIVES: Postoperative pain control started to be more investigated in the last decade, when it has been observed that postoperative analgesia was inadequate. The word preemptive implies a type of analgesia ...

Background: There are few studies reporting pain and postoperative analgesia associated with mastectomy in dogs. The aim of this study was to evaluate postoperative pain after unilateral mastectomy using two different ...

Background. The aim of this study was to test if intraoperative administration of N2O during propofol-remifentanil anaesthesia prevented the onset of postoperative opioid-induced hyperalgesia(OIH).