Buscar
Mostrando ítems 1-10 de 640
Protein-lipid interactions modulate lipid composition, membrane dynamics and structure
(Nova Science Publishers, 2018)
The interactions of proteins with membrane surfaces are important to many biological processes, including signaling, recognition, and membrane trafficking, cell division and cell structure. When the Fluid Mosaic Model (FMM) ...
Thermosensing via transmembrane protein-lipid interactions
(Elsevier Science, 2015-09)
Cell membranes are composed of a lipid bilayer containing proteins that cross and/or interact with lipids on either side of the two leaflets. The basic structure of cell membranes is this bilayer, composed of two opposing ...
Role of transmembrane proteins for phase separation and domain registration in asymmetric lipid bilayers
(2019-08-01)
It is well known that the formation and spatial correlation of lipid domains in the two apposed leaflets of a bilayer are influenced by weak lipid–lipid interactions across the bilayer’s midplane. Transmembrane proteins ...
Relevance of the protein macrodipole in the membrane-binding process. Interactions of fatty-acid binding proteins with cationic lipid membranes
(Public Library of Science, 2018-03)
The fatty acid-binding proteins L-BABP and Rep1-NCXSQ bind to anionic lipid membranes by electrostatic interactions. According to Molecular Dynamics (MD) simulations, the interaction of the protein macrodipole with the ...
Evaluation of the Defay-Prigogine model for the membrane interphase in relation to biological response in membrane-protein interactions
(Elsevier, 2013-07)
Surface water activity appears as a common factor when the interaction of several aqueous soluble and surface active proteins with lipid membranes of different composition is measured by the changes in surface pressure of ...
How cholesterol interacts with membrane proteins: an exploration of cholesterol-binding sites including CRAC, CARC, and tilted domains
(Frontiers, 2013-02-28)
The plasma membrane of eukaryotic cells contains several types of lipids displaying high biochemical variability in both their apolar moiety (e.g., the acyl chain of glycerolipids) and their polar head (e.g., the sugar ...
Molecular interactions of an ornithine-rich pH-responsive self-Assembling peptide with a model lipid membrane: Conformational aspects
(2016-09-01)
Investigating interactions of designed peptide-based biomaterials with lipid membranes is important for applications in nanobiotechnology. Here the interaction of an ornithine-rich pH-responsive peptide called P11-5 with ...
Conformational changes, from β-strand to α-helix, of the fatty acid-binding protein ReP1-NCXSQ in anionic lipid membranes: dependence with the vesicle curvature
(Springer, 2017-07)
We studied the conformational changes of the fatty acid-binding protein ReP1-NCXSQ in the interface of anionic lipid membranes. ReP1-NCXSQ is an acidic protein that regulates the activity of the Na+/Ca2+ exchanger in squid ...
The outer membrane protein A as a model for the study of lipid-protein interactions in complex neuronal membranes
(UniandesMaestría en Ingeniería BiomédicaFacultad de IngenieríaDepartamento de Ingeniería Biomédica, 2019)
Understanding the dynamics of different proteins with their lipidic environment can provide a great insight regarding the novel uses of this molecules in areas such as drug delivery systems. Here, a model for the study of ...