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L-Proline uptake in Crithidia deanei is influenced by its endosymbiont bacterium
(WILEY-BLACKWELL, 2008)
Crithidia deanei, a monoxenic trypanosomatid, presents an endosymbiotic bacterium in its cytoplasm. Both the protozoan and the bacterium maintain intensive metabolic exchange, resulting in an interesting model to study the ...
Proline metabolic dynamics and implications in drought tolerance of peanut plants
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2020-06)
Proline accumulation and metabolism are associated with mechanisms of abiotic stress avoidance in plants. Proline accumulation generally improves osmotic stress tolerance whereas proline metabolism can have varying effects ...
Proline modulates the Trypanosoma cruzi resistance to reactive oxygen species and drugs through a novel D, L-proline transporter
(Public Library of Science, 2014-03)
Trypanosoma cruzi, the etiological agent of Chagas' disease, has a metabolism largely based on the consumption of glucose and proline. This amino acid is essential for host cells infection and intracellular differentiation. ...
Evaluation of proline analogs as trypanocidal agents through the inhibition of a Trypanosoma cruzi proline transporter
(Elsevier Science, 2017-08)
Background: Trypanosoma cruzi, the etiological agent of Chagas disease, uses proline as its main carbon source, essential for parasite growth and stage differentiation in epimastigotes and amastigotes. Since proline is ...
Proline Exogenously Supplied or Endogenously Overproduced Induces Different Nutritional, Metabolic, and Antioxidative Responses in Transgenic Tobacco Exposed to Cadmium
(2021-01-01)
Proline plays adaptive roles in plant tolerance to cadmium (Cd)-induced stress, but many gaps remain to be elucidated as the responses triggered by exogenously supplied proline or endogenously overproduction are not well ...
Drought-induced proline synthesis depends on root-to-shoot communication mediated by light perception
(2018-01-01)
Proline accumulation in roots and shoots is one of the most evident responses to environmental stresses such as drought, which is currently one of the main threats for agriculture. Based on this response, in this work, we ...
Proline dehydrogenase regulates redox state and respiratory metabolism in Trypanosoma Cruzi
(Public Library of ScienceSan Francisco, 2013-07-22)
Over the past three decades, L-proline has become recognized as an important metabolite for trypanosomatids. It is involved in a number of key processes, including energy metabolism, resistance to oxidative and nutritional ...
Metabolic changes in barley seedlings at different aphid infestation levels
(1994)
Different infestation levels with the greenbug (Schizaphis graminum Rondani) were correlated with physiological parameters and several metabolite concentrations in young barley plants (Hordeum vulgare cv Aramir). Leaf water ...
The N-terminal domain of Arabidopsis proline dehydrogenase affects enzymatic activity and protein oligomerization
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2020-09)
Proline dehydrogenase (ProDH) is a flavoenzyme that catalyzes the oxidation of proline (Pro) into Δ1-pyrroline-5-carboxylate (P5C). In eukaryotes, ProDH coordinates with different Pro metabolism enzymes to control energy ...
Genome-scale reconstruction of the human astrocyte metabolic network
(Frontiers Research Foundation, 2017)