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Cloning the human pro-apoptotic BAX gene into a high-expression yeast vector designed for overexpressing genes in Yeast 2.0.
(Universidad EAFITBiologíaEscuela de Ciencias. Ciencias BásicasMedellín, 2019)
Paradoxical implication of BAX/BAK in the persistence of tetraploid cells
(Springernature, 2021)
Pro-apoptotic multi-domain proteins of the BCL2 family such as BAX and BAK are well known for their important role in the
induction of mitochondrial outer membrane permeabilization (MOMP), which is the rate-limiting step ...
Effects of Helicobacter pylori Infection on the Expressions of Bax and Bcl-2 in Patients with Chronic Gastritis and Gastric Cancer
(Springer, 2010-01-01)
The aim of the present study is to evaluate the influence of Helicobacter pylori on Bax and Bcl-2 mRNA and protein levels in patients with chronic gastritis and gastric cancer. The study included 217 patients, of which 26 ...
Effects of Helicobacter pylori Infection on the Expressions of Bax and Bcl-2 in Patients with Chronic Gastritis and Gastric Cancer
(Springer, 2010-01-01)
The aim of the present study is to evaluate the influence of Helicobacter pylori on Bax and Bcl-2 mRNA and protein levels in patients with chronic gastritis and gastric cancer. The study included 217 patients, of which 26 ...
Structural studies of the protein endostatin in fusion with BAX BH3 death domain, a hybrid that presents enhanced antitumoral activity
(2017-05-01)
Endostatin (ES) is an antiangiogenic protein that exhibits antitumor activity in animal models. However, the activity observed in animals was not observed in human clinical trials. ES-BAX is a fusion protein composed of ...
Endoplasmic Reticulum Calcium Release Engages Bax Translocation in Cortical Astrocytes
(Springer, 2011-05-01)
Apoptosis is a highly complex form of cell death that can be triggered by alterations in Ca(2+) homeostasis. Members of the Bcl-2 family may regulate apoptosis and modulate Ca(2+) distribution within intracellular compartments. ...
Diminishing apoptosis by deletion of bax or overexpression of Bcl-2 does not protect against infectious prion toxicity in vivo
(2007)
B-cell lymphoma protein 2 (Bcl-2) and Bcl-2-associated X protein (Bax), key antiapoptotic and proapoptotic proteins, respectively, have important roles in acute and chronic models of neurologic disease. Several studies ...
Bcl-2 and bax Expressions in pre-term, term and post-term placentas
(2008-08-01)
Problem: Placental apoptosis-associated protein imbalance might contribute to the pathogenesis of pre- and post-term birth. Therefore, we evaluated the expression and distribution of pro-apoptotic (Bax) and anti-apoptotic ...
Bcl-X-L inhibits Bax-induced alterations in mitochondrial respiration and calcium release
(Elsevier B.V., 2008-09-12)
Apoptosis is a natural cell elimination process involved in a number of physiological and pathological events. This process can be regulated by members of the Bcl-2 family. Bax, a pro-apoptotic member of this family, ...