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N-alkylation of poloxamines modulates micellar assembly and encapsulation and release of the antiretroviral efavirenz
(Elsevier Science, 2010-09)
Poloxamines (X-shaped poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) diblocks connected to a central ethylenediamine group) were N-methylated and N-allylated with the aim of widening their versatility as drug ...