More adults with painful diabetic neuropathy have pain relief and also adverse events with pregabalin 300 or 600 mg daily than with placebo, but researchers found no clear benefit or harm with a 150‐mg dose.Moderate‐certainty ...

Pregabalin (PGB) is extensively prescribed to treat neurological andneuropsychiatrical conditions such as neuropathic pain, anxiety disorders and epilepsy.Although PGB is known to bind selectively to the α2δ subunit of ...

More adults with postherpetic neuralgia have pain relief with pregabalin 150 to 600 mg daily than with placebo, but harms are more common with doses of 300 to 600 mg.More adults with moderate or severe postherpetic neuralgia ...

A computationally designed impedimetric pregabalin (PGB) biosensor based on immobilization of bovine serum albumin (BSA) onto graphene/glassy carbon electrode (BSA/Gr/GCE) has been developed using initial characterization ...

In this work, we studied the effects of the anticonvulsant and analgesic drug pregabalin (PGB) on excitatory postsynaptic currents (EPSCs) at principal neurons of the mouse medial nucleus of the trapezoid body and on ...

Compared with placebo for adolescents and adults with drug‐resistant focal epilepsy taking up to five antiepileptic drugs (AEDs), low‐certainty evidence suggests that more people may achieve a 50% or greater reduction in ...

Purpose: Obesity has been considered as a major public health problem in developed countries for which bariatric surgery has become an important treatment strategy. Postoperative pain, however, is a frequent problem in ...