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PPAR beta/delta and PPAR gamma maintain undifferentiated phenotypes of mouse adult neural precursor cells from the subventricular zone
(Frontiers Research Foundation, 2015)
The subventricular zone(SVZ)is one of the main niches of neural stem cells in the adult mammalian brain.
PPAR beta/delta and PPAR gamma maintain undifferentiated phenotypes of mouse adult neural precursor cells from the subventricular zone
(Frontiers Research Foundation, 2015)
The subventricular zone (SVZ) is one of the main niches of neural stem cells in the adult mammalian brain. Stem and precursor cells in this region are the source for neurogenesis and oligodendrogesis, mainly in the olfactory ...
Effects of 15-deoxy-Delta(12, 14) prostaglandin J(2) and ciglitazone on human cancer cell cycle progression and death: The role of PPAR gamma
(ELSEVIER SCIENCE BV, 2008)
The role of PPAR-gamma in ciglitazone and 15-d PGJ(2)-induced apoptosis and cell cycle arrest of Jurkat (before and after PPAR gamma gene silencing), U937 (express high levels of PPAR gamma) and HeLa (that express very low ...
Medium Chain Fatty Acids Are Selective Peroxisome Proliferator Activated Receptor (PPAR) gamma Activators and Pan-PPAR Partial Agonists
(Public Library Science, 2012-05-23)
Thiazolidinediones (TZDs) act through peroxisome proliferator activated receptor (PPAR) gamma to increase insulin sensitivity in type 2 diabetes (T2DM), but deleterious effects of these ligands mean that selective modulators ...
New PPAR alpha/gamma/delta Optimal Activator Rationally Designed by Computational Methods
(Soc Brasileira Quimica, 2016-09-01)
The peroxisome proliferator-activated receptor gamma (PPAR gamma) is a nuclear receptor that acts as a transcription factor, regulating glucose, lipid and inflammation signaling and it is exploited in type 2 diabetes ...
Ppar alpha and ppar gamma regulate the nucleoside transporter hent1
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2012)
Structural requirement for PPAR gamma binding revealed by a meta analysis of holo-crystal structures
(ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2010)
PPAR gamma is a ligand regulated transcriptional factor that modulates the transcription of several genes involved in fat and sugar metabolism. Due to its easy bacterial expression and crystallization, several crystal ...