Buscar
Mostrando ítems 1-10 de 415
Exploring in silico transcriptional and post-transcriptional gene regulatory networks in the Corynebacterium genus
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE BIOLOGIA GERALPrograma de Pós-Graduação em BioinformaticaUFMG, 2021-05-27)
Transcriptional and post-transcriptional regulation of gene expression are considered key regulatory steps in bacteria. Regulatory molecules such as transcription factors (TF), sigma-factors and small RNAs (sRNAs) modulate ...
Transcription rate modulation through the Trypanosoma cruzi life cycle occurs in parallel with changes in nuclear organisation
(Elsevier B.V., 2001-01-15)
In trypanosomes transcription occurs as large polycistronic units, with trans-splicing and polyadenylation generating each individual mRNA. There are no defined RNA. polymerase II promoters and mRNA stabilisation is most ...
Circadian oscillation and development-dependent expression of glycine-rich RNA binding proteins in tomato fruits
(Csiro Publishing, 2014-01)
Glycine-rich RNA-binding proteins (GRPs) are involved in the modulation of the post-transcriptional processing of transcripts and participate as an output signal of the circadian clock. However, neither GRPs nor the circadian ...
Multiple mechanisms of growth hormone-regulated gene transcription
(Elsevier, 2007)
Diverse physiological actions of growth hormone (GH) are mediated by changes in gene transcription. Transcription can be regulated at several levels, including post-translational modification of transcription factors, and ...
Liver glucokinase: An overview on the regulatorymechanisms of its activity
(John Wiley & Sons Inc, 2011-01)
Blood glucose is the primary cellular substrate and in vivo must be tightly maintained. The liver plays a key role in glucose homeostasis increasing or decreasing glucose output and uptake during fasting and feeding. ...
Mir-351-5p contributes to the establishment of a pro-inflammatory environment in the H9c2 cell line by repressing PTEN expression
(Springer, 2016-01-01)
The activated renin-angiotensin-aldosterone system modulates several metabolic pathways that contribute to left ventricular hypertrophy and heart failure. In this metabolic system, angiotensin II modulates heart ...
Transcriptional patterns of Coffea arabica L. nitrate reductase, glutamine and asparagine synthetase genes are modulated under nitrogen suppression and coffee leaf rust
(2020-01-01)
This study evaluated the transcriptional profile of genes related to nitrogen (N) assimilation in coffee plants susceptible and resistant to rust fungi under N sufficiency and N suppression. For this purpose, we inoculated ...
Introduction to transcription factor structure and function
(Elsevier, 2015)
Transcription of eukaryotic genes is regulated by DNA binding proteins known as transcription factors. These factors interact specifically with sequences located in the promoter regions of the genes they regulate. Transcription ...
Neighboring gene regulation by antisense long Non-Coding RNAs
(2015)
Antisense transcription, considered until recently as transcriptional noise, is a very common phenomenon in human and eukaryotic transcriptomes, operating in two ways based on whether the antisense RNA acts in cis or in ...
MAP kinase phosphatase-3 (MKP-3) is transcriptionally and post-translationally up-regulated by hCG and modulates cAMP-induced p21 expression in MA-10 Leydig cells
(Elsevier Ireland, 2013-07)
Abstract Luteinizing hormone (LH) activates ERK1/2, MAP kinases (MAPK) necessary for its action on steroidogenesis and cell proliferation, and also induces MAPK phosphatase-1 (MKP-1), which rapidly dephosphorylates nuclear ...