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Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA
(National Academy of Sciences, 2012-05)
The checkpoint kinases Chk1 and ATR are broadly known for their role in the response to the accumulation of damaged DNA. Because Chk1 activation requires its phosphorylation by ATR, it is expected that ATR or Chk1 ...