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Intranasal delivery of zidovudine by PLA and PLA-PEG blend nanoparticles
(Elsevier B.V., 2010-08-16)
This study describes the preparation and evaluation of biodegradable poly(L-lactide) (PLA) and poly(L, lactide)-poly(ethylene glycol) (PLA-PEG) blend nanoparticles containing zidovudine as model drug. The prepared nanoparticles ...
Intranasal delivery of zidovudine by PLA and PLA-PEG blend nanoparticles
(Elsevier B.V., 2010-08-16)
This study describes the preparation and evaluation of biodegradable poly(L-lactide) (PLA) and poly(L, lactide)-poly(ethylene glycol) (PLA-PEG) blend nanoparticles containing zidovudine as model drug. The prepared nanoparticles ...
Desenvolvimento de nanopartículas de PLA e PLA-PEG para administração intranasal de zidovudina
(Universidade Estadual Paulista (Unesp), 2007-04-04)
A zidovudina (AZT) é um fármaco amplamente usado no tratamento da síndrome da imunodeficiência adquirida. O AZT apresenta baixa biodisponibilidade oral pois sofre rápido e extenso metabolismo de primeira passagem hepática, ...
Desenvolvimento de nanopartículas de PLA e PLA-PEG para administração intranasal de zidovudina
(Universidade Estadual Paulista (Unesp), 2007-04-04)
A zidovudina (AZT) é um fármaco amplamente usado no tratamento da síndrome da imunodeficiência adquirida. O AZT apresenta baixa biodisponibilidade oral pois sofre rápido e extenso metabolismo de primeira passagem hepática, ...
Nanoencapsulation and Characterization of Zidovudine on Poly(L-lactide) and Poly(L-lactide)-Poly(ethylene glycol)-Blend Nanoparticles
(Amer Scientific Publishers, 2012-11-01)
In this work, the antiretroviral zidovudine was encapsulated on biodegradable poly(L-lactide) (PLA) or poly(L-lactide)-poly(ethylene glycol) (PLA-PEG)-blend nanoparticles by the double-emulsion solvent-evaporation method. ...
Nanoencapsulation and Characterization of Zidovudine on Poly(L-lactide) and Poly(L-lactide)-Poly(ethylene glycol)-Blend Nanoparticles
(Amer Scientific Publishers, 2012-11-01)
In this work, the antiretroviral zidovudine was encapsulated on biodegradable poly(L-lactide) (PLA) or poly(L-lactide)-poly(ethylene glycol) (PLA-PEG)-blend nanoparticles by the double-emulsion solvent-evaporation method. ...
Desenvolvimento de nanopartículas de PLA e PLA-PEG para administração intranasal de zidovudina
(Universidade Estadual Paulista (UNESP), 2014)
Intranasal delivery of zidovudine by PLA and PLA-PEG blend nanoparticles
(Elsevier B.V., 2014)
Zidovudine-Loaded PLA and PLA-PEG Blend Nanoparticles: Influence of Polymer Type on Phagocytic Uptake by Polymorphonuclear Cells
(John Wiley & Sons Inc, 2009-01-01)
Mononuclear (macrophages) and polymorphonuclear leucocytes cells play an important role in the immunopathogenesis of acquired immunodeficiency syndrome. Zidovudine is a broad-spectrum drug used in current antiretroviral ...
Zidovudine-Loaded PLA and PLA-PEG Blend Nanoparticles: Influence of Polymer Type on Phagocytic Uptake by Polymorphonuclear Cells
(John Wiley & Sons Inc, 2009-01-01)
Mononuclear (macrophages) and polymorphonuclear leucocytes cells play an important role in the immunopathogenesis of acquired immunodeficiency syndrome. Zidovudine is a broad-spectrum drug used in current antiretroviral ...