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PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K

Babraham Institute; Akita University Graduate School of Medicine; University of Dundee; CRUK Cambridge Institute; Universidade Estadual Paulista (Unesp); Refractory Respiratory Inflammation Discovery Performance Unit (2017-11-02)

The PI3K signaling pathway regulates cell growth and movement and is heavily mutated in cancer. Class I PI3Ks synthesize the lipid messenger PI(3,4,5)P3. PI(3,4,5)P3 can be dephosphorylated by 3- or 5-phosphatases, the ...

Inibição da via PI3K na leucemia linfoide aguda T pediátrica = resposta à quimioterapia e implicações clínicas = PI3K inhibition in childhood T-cell acute lymphoblastic leukemia: response to chemotherapy and clinical implicationsPI3K inhibition in childhood T-cell acute lymphoblastic leukemia : response to chemotherapy and clinical implications

Silveira, André Bortolini, 1987- ([s.n.], 2013)

THE ROLE OF PI3K SOMATIC POINT MUTATIONS AND DOWNSTREAM PROTEIN EXPRESSION OF PI3K/AKT/MTOR PATHWAY IN GALLBLADDER CARCINOMA.

Autor desconocido (2015)

Papel de la vía fosfatidilinositol 3 kinasa (PI3K/Akt) en humanos

Pinzón, Carlos Eduardo; Serrano, Martha Lucía; Sanabria, María (Universidad del RosarioEscuela de Medicina y Ciencias de la Salud, 2010)

The signaling pathway of phosphatidylinositol 3-kinase (PI3K) is critical in many aspects of growth and cell survival. The path of PI3K is stimulated physiologically as a result of many growth factors and regulatory factors. ...

[en] AMPLITUDE ANALYSIS OF THE DECAY D+ K (PI)-(PI)+(PI)+ IN FOCUS EXPERIMENT[pt] ANÁLISE DE AMPLITUDES DO DECAIMENTO D+ KS(PI)-(PI)+(PI)+ NO EXPERIMENTO FOCUS

JUAN MARTIN OTALORA GOICOCHEA

Acute physical exercise increases APPL1/PI3K signaling in the hypothalamus of lean mice

Universidade Estadual de Campinas (UNICAMP); Universidade Estadual Paulista (Unesp); Universidade de São Paulo (USP) (2019-01-01)

Adiponectin is an adipokine that acts in the control of energy homeostasis. The adaptor protein containing the pleckstrin homology domain, phosphotyrosine-binding domain, and leucine zipper motif 1 (APPL1) is a key protein ...

PI- Álgebras e Crescimento Polinomial das CodimensõesPI-Álgebras and Polynomial Growth of the Codimensions

Gouveia, Tatiana Aparecida (Universidade Federal de Viçosa, 2016)

Search for the Rare Decays K-L -> pi(0)pi(0)mu(+)mu(-) and K-L -> pi(0)pi X-0(0) -> pi(0)pi(0)mu(+)mu(-)

Abouzaid, E; Arenton, M; Barker, AR; Bellantoni, L; Blucher, E; Bock, GJ; Cheu, E; Coleman, R; Corcoran, MD; Cox, B; Erwin, AR; Escobar, CO; Glazov, A; Golossanov, A; Gomes, RA; Gouffon, P; Hsiung, YB; Jensen, DA; Kessler, R; Kotera, K; Ledovskoy, A; McBride, PL; Monnier, E; Nguyen, H; Niclasen, R; Phillips, DG; Ping, H; Ramberg, EJ; Ray, RE; Ronquest, M; Santos, E; Slater, W; Smith, D; Solomey, N; Swallow, EC; Toale, PA; Tschirhart, R; Velissaris, C; Wah, YW; Wang, J; White, HB; Whitmore, J; Wilking, MJ; Winston, R; Worcester, ET; Worcester, M; Yamanaka, T; Zimmerman, ED; Zukanovich, RF (Amer Physical SocCollege PkEUA, 2011)

Participação da Fosfatidilinositol 3-quinase no modelo murino de infecção pelo dengue virus sorotipo 3

Deborah Fernandes Valadão (Universidade Federal de Minas GeraisUFMG, 2013-02-07)

Dengue is one of the most important mosquito-borne diseases affecting humans nowadays. It has become a great concern to public health system, given the incidence of the disease caused by dengue virus (DENV) has increased ...

PI3K/AKT pathway is altered in the endometriosis patient’s endometrium and presents differences according to severity stage

Madanes, Daniela; Bilotas, Mariela Andrea; Bastón, Juan Ignacio; Singla, José Javier; Meresman, Gabriela Fabiana; Barañao, Rosa Inés; Ricci, Analía Gabriela (Informa Healthcare, 2019-10)

Based on the inflammatory nature and hormone-dependency of endometriosis, PI3K/AKT signaling appears to influence its progression. Could the endometriosis stages be linked to differential changes in PI3K/AKT pathway ...

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