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Signal transduction events mediating chitosan stimulation of anthraquinone synthesis in Rubia tinctorum
(Elsevier Ireland, 2004-12)
The signalling mechanism by which chitosan increases anthraquinones in Rubia tinctorum L. is largely unknown. We recently showed that the effects of the elicitor require activation of the PLC/PKC cascade. In view of the ...
Purinergic (ATP) signaling stimulates JNK1 but not JNK2 MAPK in osteoblast-like cells: Contribution of intracellular Ca2+ release, stress activated and L-voltage-dependent calcium influx, PKC and Src kinases
(Elsevier Science Inc, 2008-09-15)
This work shows that ATP activates JNK1, but not JNK2, in rat osteoblasts and ROS-A 17/2.8 osteoblast-like cells. In ROS-A 17/2.8 cells ATP induced JNK1 phosphorylation in a dose- and time-dependent manner. JNK1 phosphorylation ...
Modulation of ERK1/2 and p38 MAPK signaling pathway by ATP in osteoblasts: involvement of mechanical stress-activated calcium influx, PKC and Src activation
(Pergamon-Elsevier Science Ltd, 2006-12)
There is evidence that extracellular nucleotides, acting through multiple P2 receptors, may play an important role in the regulation of bone metabolism by activating intracellular signaling cascades. We have studied the ...
Signal transduction pathways involved in non-genomic action of estrone on vascular tissue
(Elsevier Science Inc, 2006-10)
Previously we demonstrated that estrone non-genomically regulates rat aortic NOS and COX activity and that this effect depends on ovarian activity. The purpose of the present study was to characterize this effect and ...
Molecular aspects of the early stages of elicitation of secondary metabolites in plants
(Elsevier Ireland, 2007-05)
Plants are a source of commercially important secondary metabolites. Elicitation of plant cells in culture represents a useful biotechnological tool to improve the production of these valuable metabolites. Greater knowledge ...
Potencial terapêutico do extrato metanólico de Condalia buxifolia reissek no controle da dor aguda: estudo do mecanismo de ação
(Universidade Federal de Santa MariaBRFarmacologiaUFSMPrograma de Pós-Graduação em Farmacologia, 2015-08-06)
The medicinal plant Condalia buxifolia has been traditionally used to treat inflammatory processes. The present study aimed to evaluate the phytochemical profile and the analgesic effect of the methanolic extract from the ...