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Advances in nanotechnology-based drug delivery in targeting PI3K signaling in respiratory diseases
(FUTURE MEDICINE LTD, 2021)
Functionalization of gold nanoparticles with two aminoalcohol-based quinoxaline derivatives for targeting phosphoinositide 3-kinases (PI3Kα)
(Royal Society of Chemistry (RSC), 2018-12-17)
A cascata dos fosfoinositídeosThe phosphoinositide cascate
(-Brasil-, 2019)
The activation loop of PKA catalytic isoforms is differentially phosphorylated by Pkh protein kinases in Saccharomyces cerevisiae
(Portland Press, 2012-09)
PDK1 (phosphoinositide-dependent protein kinase 1) phosphorylates and activates PKA (cAMP-dependent protein kinase) in vitro. Docking of the HM (hydrophobic motif) in the C-terminal tail of the PKA catalytic subunits on ...
c-Jun regulates phosphoinositide-dependent kinase 1 transcription: implication for Akt and protein kinase C activities and melanoma tumorigenesis
(American Society For Biochemistry And Molecular Biology, 2010-01-08)
utations in N-RAS and B-RAF, which commonly occur in melanomas, result in constitutive activation of the mitogen-activated protein kinase (MAPK)/extracellular signal-regulated protein kinase (ERK) signaling. Active ERK ...
Prominin-1 (CD133) modulates the architecture and dynamics of microvilli
(Wiley Blackwell Publishing, Inc, 2018-11-14)
Prominin-1 is a cell surface biomarker that allows the identification of stem and cancer stemcells from different organs. It is also expressed in several differentiated epithelial and non-epithelial cells. Irrespective of ...