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Differences in phosphatidic acid signalling and metabolism between ABA and GA treatments of barley aleurone cells
(Elsevier Masson, 2013-02)
Phosphatidic acid (PA) is the common lipid product in abscisic acid (ABA) and gibberellic acid (GA)response. In this work we investigated the lipid metabolism in response to both hormones. We could detect an in vivo ...
Involvement of Lysophosphatidic Acid, Sphingosine 1-Phosphate and Ceramide 1-Phosphate in the Metabolization of Phosphatidic Acid by Lipid Phosphate Phosphatases in Bovine Rod Outer Segments
(Springer/Plenum Publishers, 2008-07)
The aim of the present research was to evaluate the generation of [2-3H]diacylglycerol ([2-3H]DAG) from [2-3H]-Phosphatidic acid ([2-3H]PA) by lipid phosphate phosphatases (LPPs) at different concentrations of lysophosphatidic ...
Identification and physiological characterization of phosphatidic acid phosphatase enzymes involved in triacylglycerol biosynthesis in Streptomyces coelicolor
(Biomed Central, 2013-01)
BACKGROUND: Phosphatidic acid phosphatase (PAP, EC 3.1.3.4) catalyzes the dephosphorylation of phosphatidate yielding diacylglycerol (DAG), the lipid precursor for triacylglycerol (TAG) biosynthesis. Despite the importance ...
Regulation of Phosphatidic Acid Metabolism by Sphingolipids in the Central Nervous System
(Hindawi Publishing Corporation, 2011-01)
This paper explores the way ceramide, sphingosine, ceramide 1-phosphate, and sphingosine 1-phosphate modulate the generation of second lipid messengers from phosphatidic acid in two experimental models of the central nervous ...
The catalytic efficiency of Lipin 1beta increases by physically interacting with the protooncoprotein c-Fos
(American Society For Biochemistry And Molecular Biology, 2015-10)
Phosphatidic acid (PA) is a central precursor for membrane phospholipid biosynthesis. Lipin family is a Mg-dependent type I PA phosphatase,involved in de novo synthesis of neutral lipids and of phospholipids. The regulation ...
Differential phosphatidic acid metabolism in barley leaves and roots induced by chilling temperature
(Elsevier France-editions Scientifiques Medicales Elsevier, 2018-11)
Phosphatidic acid (PA) is an important bioactive lipid that mediates chilling responses in barley. Modifications in the lipid composition of cellular membranes during chilling are essential to maintain their integrity and ...
Characterization of key enzymes involved in triacylglycerol biosynthesis in mycobacteria
(Scientific Reports, 2022)
Phosphatidic acid metabolism in rat liver cell nuclei
(Elsevier Science, 2013-02-21)
The aim of the present research was to analyze the pathways for phosphatidic acid metabolism in purified nuclei from liver. Lipid phosphate phosphatase, diacylglycerol lipase, monoacylglycerol lipase and PA-phospholipase ...
Insulin Action on Polyunsaturated Phosphatidic Acid Formation in Rat Brain: An “In Vitro” Model with Synaptic Endings from Cerebral Cortex and Hippocampus
(Springer/Plenum Publishers, 2009-12)
The highly efficient formation of phosphatidic acid from exogenous 1-stearoyl-2-arachidonoyl-sn-glycerol (SAG) in rat brain synaptic nerve endings (synaptosomes) from cerebral cortex and hippocampus is reported. Phosphatidic ...
Metabolic pathways for the degradation of phosphatidic acid in isolated nuclei from cerebellar cells
(Elsevier, 2011-03)
The aim of the present research was to analyse the pathways for phosphatidic acid metabolism in purified nuclei from cerebellar cells. Lipid phosphate phosphatase and diacylglyceride lipase activities were detected in ...