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Differences in phosphatidic acid signalling and metabolism between ABA and GA treatments of barley aleurone cells
(Elsevier Masson, 2013-02)
Phosphatidic acid (PA) is the common lipid product in abscisic acid (ABA) and gibberellic acid (GA)response. In this work we investigated the lipid metabolism in response to both hormones. We could detect an in vivo ...
Regulation of Phosphatidic Acid Metabolism by Sphingolipids in the Central Nervous System
(Hindawi Publishing Corporation, 2011-01)
This paper explores the way ceramide, sphingosine, ceramide 1-phosphate, and sphingosine 1-phosphate modulate the generation of second lipid messengers from phosphatidic acid in two experimental models of the central nervous ...
Differential modulation of phospholipase D and phosphatidate phosphohydrolase during aging in rat cerebral cortex synaptosomes
(Pergamon-Elsevier Science Ltd, 2002-04-01)
Phosphatidylcholine (PC) hydrolysis generates two important second messengers: phosphatidic acid (PA) and diacylglycerol (DAG). Phospholipase D (PLD) and phosphatidate phosphohydrolase (PAPase) are involved in their ...
Phosphatidic acid metabolism in rat liver cell nuclei
(Elsevier Science, 2013-02-21)
The aim of the present research was to analyze the pathways for phosphatidic acid metabolism in purified nuclei from liver. Lipid phosphate phosphatase, diacylglycerol lipase, monoacylglycerol lipase and PA-phospholipase ...
Insulin Action on Polyunsaturated Phosphatidic Acid Formation in Rat Brain: An “In Vitro” Model with Synaptic Endings from Cerebral Cortex and Hippocampus
(Springer/Plenum Publishers, 2009-12)
The highly efficient formation of phosphatidic acid from exogenous 1-stearoyl-2-arachidonoyl-sn-glycerol (SAG) in rat brain synaptic nerve endings (synaptosomes) from cerebral cortex and hippocampus is reported. Phosphatidic ...
Aging promotes a different phosphatidic acid utilization in cytosolic and microsomal fractions from brain and liver
(Pergamon-Elsevier Science Ltd, 2001-08)
Among the morphological and biochemical changes taking place in the membranes of aged tissues, we reported in previous studies on alterations in phospholipid synthesis and phospholipid-specific fatty acid composition. ...
The catalytic efficiency of Lipin 1beta increases by physically interacting with the protooncoprotein c-Fos
(American Society For Biochemistry And Molecular Biology, 2015-10)
Phosphatidic acid (PA) is a central precursor for membrane phospholipid biosynthesis. Lipin family is a Mg-dependent type I PA phosphatase,involved in de novo synthesis of neutral lipids and of phospholipids. The regulation ...
Differential phosphatidic acid metabolism in barley leaves and roots induced by chilling temperature
(Elsevier France-editions Scientifiques Medicales Elsevier, 2018-11)
Phosphatidic acid (PA) is an important bioactive lipid that mediates chilling responses in barley. Modifications in the lipid composition of cellular membranes during chilling are essential to maintain their integrity and ...
Metabolic pathways for the degradation of phosphatidic acid in isolated nuclei from cerebellar cells
(Elsevier, 2011-03)
The aim of the present research was to analyse the pathways for phosphatidic acid metabolism in purified nuclei from cerebellar cells. Lipid phosphate phosphatase and diacylglyceride lipase activities were detected in ...
Mitochondrial acyltransferases and glycerophospholipid metabolism
(Elsevier Science, 2017-01)
Our understanding of the synthesis and remodeling of mitochondrial phospholipids remains incomplete. Two isoforms of glycerol-3-phosphate acyltransferase (GPAT1 and 2) and two isoforms of acylglycerol-3-phosphate acyltransferase ...