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Evaluation of the slip length in the slipping friction between background electrolytes and peptides through the modeling of their capillary zone electrophoretic mobilities
(Wiley Vch Verlag, 2013-09)
This work analyzes and discusses several physicochemical peptide chain properties that may generate partial or total BGE slip boundary conditions on the surface of peptides migrating as spherical and aspherical particles ...
Charge regulation phenomenon predicted from the modeling of polypeptide electrophoretic mobilities as a relevant mechanism of amyloid-beta peptide oligomerization
(Wiley VCH Verlag, 2016-03)
Electrophoretic mobilities of amyloid-beta (1-40) and (1-42) peptides and their aggregates are modeled to study the amyloidogenic pathway associated with Alzheimer´s Disease. The near molecule pH generated by the intraparticle ...
Estimation of Global Structural and Transport Properties of Peptides through the Modeling of their CZE Mobility Data
(Wiley VCH Verlag, 2010-08)
Peptide electrophoretic mobility data are interpreted through a physicochemical CZE model, providing estimates of the equivalent hydrodynamic radius, hydration, effective and total charge numbers, actual ionizing pK, pH-near ...
Global properties and propensity to dimerization of the amyloid-beta (12-28) peptide fragment through the modeling of its monomer and dimer diffusion coefficients and electrophoretic mobilities
(Wiley, 2015-03)
Neuronal activity loss may be due to toxicity caused mainly by amyloid-beta (1–40) and (1–42) peptides forming soluble oligomers. Here the amyloid-beta (12–28) peptide fragment (monomer) and its dimer are characterized at ...
Estimation of electrokinetic and hydrodynamic global properties of relevant amyloid-beta peptides through the modeling of their effective electrophoretic mobilities and analysis of their propensities to aggregation
(Wiley VCH Verlag, 2014-07)
Neuronal activity loss may be due to toxicity caused by amyloid-beta peptides forming soluble oligomers. Here amyloid-beta peptides (1–42, 1–40, 1–39, 1–38, and 1–37) are characterized through the modeling of their ...
Prevention of in vitro oxidation of low density lipoproteins (LDL) by amaranth peptides released by gastrointestinal digestion
(Elsevier, 2017-07)
The objective of this work was to analyze the capacity of amaranth peptides generated by gastrointestinal digestion to prevent LDL oxidation. A simulated gastrointestinal digest from protein isolate (Id); Id fractions ...
Study of peptide–ligand interactions in open-tubular capillary columns covalently modified with porphyrins
(Wiley VCH Verlag, 2011-10)
The inner surface of fused silica capillaries has been covalently modified with different porphyrins (deuteroporphyrin, complexes of deuteroporphyrin with metal ions Fe(III), Cu(II), Zn(II), Ni(II), and Cu(II)–meso–tetra ...
Signal peptide recognition in Trypanosoma cruzi GP82 adhesin relies on its localization at protein N-terminus
(NATURE PUBLISHING GROUP, 2019)
Trypanosoma cruzi, the causative agent of Chagas disease, has a dense coat of GPI-anchored virulence factors. T. cruzi GPI-anchored adhesin GP82 is encoded by a repertoire of transcripts containing several in-frame initiation ...