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Characterization of Articaine-Loaded Poly(epsilon-caprolactone) Nanocapsules and Solid Lipid Nanoparticles in Hydrogels for Topical Formulations
(Amer Scientific Publishers, 2018-06-01)
This work describes the development of poly-epsilon-caprolactone nanocapsules (PCL-NC) and solid lipid nanoparticles (SLN) aiming delivery for articaine (ATC), in order to improve its chemical stability in semi-solid ...
Nanopartículas contendo propionato de clobetasol: preparação, caracterização e incorporação em hidrogéis
(Universidade Federal de Santa MariaBRFarmacologiaUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2010-03-29)
The aim of this work was the development of nanostructured formulations containing
clobetasol propionate. Initially, it was validated a chromatographic method to assay clobetasol
propionate in nanocapsule suspensions. ...
A mechanistic view of interactions of a nanoherbicide with target organism
(American Chemical Society, 2019-04-01)
Atrazine is one of the most used herbicides and has been associated with persistent surface and groundwater contamination, and novel formulations derived from nanotechnology can be a potential solution. We used poly-epsilon ...
Poly(epsilon-caprolactone)nanocapsules as carrier systems for herbicides: Physico-chemical characterization and genotoxicity evaluation
(Elsevier B.V., 2012-09-15)
The toxicity of herbicides used in agriculture is influenced by their chemical stability, solubility, bioavailability, photodecomposition, and soil sorption. Possible solutions designed to minimize toxicity include the ...
Desenvolvimento de nanocápsulas de poli-ε-caprolactona contendo o herbicida atrazina
(Sociedade Brasileira de Química, 2012-01-01)
DEVELOPMENT of NANOCAPSULES of POLY-epsilon-CAPROLACTONE CONTAINING HERBICIDE ATRAZINE. In this study, polymeric nanocapsules of PCL containing the herbicide atrazine were prepared. In order to optimize the preparation ...
Desenvolvimento de nanocápsulas poliméricas para liberação pulmonar do dipropionato de beclometasona
(Universidade Federal de Santa MariaBRFarmáciaUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2013-03-22)
Polymeric nanocapsules have been studied extensively for drug delivery by various routes of administration. Currently, the nanoencapsulation of drugs is considered the most efficient means of ensuring controlled release, ...
Mucoadhesive Amphiphilic Methacrylic Copolymer-Functionalized Poly(epsilon-caprolactone) Nanocapsules for Nose-to-Brain Delivery of Olanzapine
(Amer Scientific Publishers, 2015-08-01)
Nose-to-brain drug delivery has been proposed to overcome the low absorption of drugs in central nervous system due to the absence of brain-blood barrier in the olfactory nerve pathway. However, the presence of a mucus ...
Desenvolvimento de nanocápsulas de poli-ε-caprolactona contendo o herbicida atrazina
(2012-04-26)
In this study, polymeric nanocapsules of PCL containing the herbicide atrazine were prepared. In order to optimize the preparation conditions, a 2 3 factorial design was performed using different formulations of nanocapsules, ...
Development of hydrophilic nanocarriers for the charged form of the local anesthetic articaine
(Elsevier B.V., 2014-09-01)
One of the current challenges in drug encapsulation concerns the development of carrier systems for hydrophilic compounds. Potential carriers include nanocapsules prepared with amphiphilic polymers, which consist of a ...
Desenvolvimento de sistemas nanoestruturados à base de óleo de pracaxi contendo ubiquinona e avaliação da citotoxicidade in vitro
(Universidade Federal de Santa MariaBRFarmáciaUFSMPrograma de Pós-Graduação em Ciências Farmacêuticas, 2014-03-27)
This work aimed the preparation of novel nanocapsules and nanoemulsions based on pracaxy oil loaded with ubiquinone. For nanocapsules, poly(-caprolactone) (PCL) or Eudragit® EPO were employed in the preparation. For ...