Buscar
Mostrando ítems 1-10 de 118
Inhibition of Poly(ADP-Ribose)Glycohydrolase activity affects lysosomal function and hampers T. cruzi infection in Vero cells
(Genetics Society of America, 2020)
Chagas disease is a potentially life-threatening protozoan infection but, despite its high incidence and large economic costs associated to it, effective pharmacological treatments are lacking. The search for new anti-chagasic ...
Clonado, caracterización y estudios funcionales de las enzimas poli (ADP-ribosa)polimerasa y poli (ADP-ribosa) glicohidrolasa de Trypanosoma bruceiCloning, characterization and functional studies of poly (ADP-ribose) polymerase and poly (ADP-ribose) glycohydrolase enzimes of Trypanosoma brucei
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2015)
Diurnal and annual evolution of UV, PAR and NIR irradiations in Botucatu/Brazil
(Elsevier B.V., 2014-01-01)
This paper describes statistical and climatic analyses of G, UV, PAR and NIR irradiations, and UV/G, PAR/G and NIR/G fractions using a data base obtained from 2001 to 2005 in Botucatu/SP/Brazil. Values of irradiations and ...
Disrupted ADP-ribose metabolism with nuclear Poly (ADP-ribose) accumulation leads to different cell death pathways in presence of hydrogen peroxide in procyclic Trypanosoma brucei
(BioMed Central, 2016-03)
Poly(ADP-ribose) (PAR) metabolism participates in several biological processes such as DNA damage signaling and repair, which is a thoroughly studied function. PAR is synthesized by Poly(ADP-ribose) polymerase (PARP) and ...
Host Cell Poly(ADP-ribose) glycohydrolase Is Crucial for Trypanosoma cruzi Infection Cycle
(Public Library Science, 2013-06-12)
Trypanosoma cruzi, etiological agent of Chagas´ disease, has a complex life cycle which involves the invasion of mammalian host cells, differentiation and intracellular replication. Here we report the first insights into ...
Diurnal and annual evolution of UV, PAR and NIR irradiations in Botucatu/Brazil
(Elsevier B.V., 2015)
Poly(ADP-ribose) metabolism in human parasitic protozoa
(Elsevier Science, 2020-08-22)
Poly(ADP-ribosyl)ation reactions constitute a post-translational protein modification synthesized in higher eukaryotes by a family of poly(ADP-ribose)polymerases (PARP) and catabolized mainly by poly(ADP-ribose) glycohydrolase ...
Analysis of anti-Müllerian hormone (AMH) and its receptor (AMHR2) genes in patients with persistent Müllerian duct syndromePesquisa de mutações nos genes do hormônio antiMülleriano (AMH) e do seu receptor (AMHR2) em pacientes com síndrome de persistência dos ductos Müllerianos
(Sociedade Brasileira de Endocrinologia e Metabologia, 2012)