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Characteristics, Properties and Analytical Methods of Paclitaxel: A Review
(2018-03-04)
Paclitaxel is a diterpenoid pseudoalkaloid, isolated from Taxus brevifolia, and is largely used as an antitumoral drug. The formulation of paclitaxel known as Taxol® employs a mixture of Cremophor EL and dehydrated ethanol, ...
Obtenção e caracterização de microesferas de copolímero PLDLA contendo paclitaxel
(Universidade Federal de São CarlosBRUFSCarPrograma de Pós-Graduação em Ciência dos Materiais - PPGCM-So, 2013-02-05)
In order to minimize the side effects of chemotherapy concurrently with the enhancement of its therapeutic action is to use it on devices that enable a controlled drug release, by vectors, such as polymeric microspheres, ...
Use of cholesterol-rich nanoparticles that bind to lipoprotein receptors as a vehicle to paclitaxel in the treatment of breast cancer: pharmacokinetics, tumor uptake and a pilot clinical study
(SPRINGER, 2009)
Purpose In animal experiments paclitaxel oleate associated with a cholesterol-rich nanoemulsion concentrated in the neoplastic tissues and showed reduced toxicity and increased antitumor activity compared with paclitaxel-Cremophor ...
Curcumin and paclitaxel induce cell death in breast cancer cell lines
(Spandidos Publications, 2018)
Breast cancer is one of the major health issues confronting women; however, treatment with conventional chemotherapeutic drugs is limited. Currently, paclitaxel is used as a therapeutic clinical agent to treat breast cancer ...
Curcumin and paclitaxel induce cell death in breast cancer cell lines
(2018)
Breast cancer is one of the major health issues confronting women; however, treatment with conventional chemotherapeutic drugs is limited. Currently, paclitaxel is used as a therapeutic clinical agent to treat breast cancer ...
Curcumin and paclitaxel induce cell death in breast cancer cell lines
(Spandidos Publications, 2019)
Síntese de derivados glicosiltriazólicos de paclitaxel como potenciais antitumorais
(Universidade Federal de Minas GeraisUFMG, 2018-02-28)
Neoplasias are associated with an uncontrolled growth of cells, resulting from risk factors called carcinogenic agents, being one of the biggest causes of death in the world. The high extent of the disease and the variety ...